madrigalpharma.com website review

Your mobile performance score is 74 (desktop: 93). Pages that score under 90 lose visitors before the first paint.

About 343 KiB of JavaScript is downloaded but never used on this page. Google estimates it would make the page about 450 ms faster on a phone.

3 images could be 51 KiB smaller with modern formats (WebP or AVIF) and sizes that fit a phone screen. Google estimates it would make the page about 350 ms faster on a phone.

Google Tag Manager costs a phone 271 ms of main-thread work and 465 KiB of downloads while your page loads. Loading it after the page is usable, or only on the pages that need it, takes that off the critical path.

7 third-party services load with your homepage (Google Tag Manager, Usercentrics CMP and JSDelivr CDN and others), adding 853 KiB and 473 ms of main-thread time.

9 files are served with short cache lifetimes, so returning visitors download them again (75 KiB).

50 KiB could be saved by minifying JavaScript.

Polyfills for old browsers add 11 KiB JavaScript that modern phones do not need. Google estimates it would make the page about 150 ms faster on a phone.

3 files block the first paint until they finish downloading. Deferring or inlining them could save about 150 ms.

4 long tasks block the main thread while loading, the longest for 84 ms. During a long task the page ignores taps.

About 67 KiB of CSS is downloaded but never applied on this page.

Critical files load one after another instead of in parallel (3 chains). Preconnecting to key origins and preloading the hero image shortens the chain.

4 KiB could be saved by minifying CSS.

Your largest element takes 6.1 s to render on a phone. Google's threshold for “good” is 2.5 s. The largest element is the element shown below.

The page becomes fully interactive after 9.6 s. Good is under 3.8 s.

The first text or image appears after 2.1 s on a phone. Good is under 1.8 s.

Visually, the page fills in at 3.8 s (Speed Index). Good is under 3.4 s.

Over the last 25 four-week periods to 2026-10-17, real Chrome visitors' tap response (inp) went from 87 ms to 85 ms at the 75th percentile (Chrome UX Report (opens in a new tab) history).

2 images (138 KiB) are JPEG, PNG or GIF. The same pictures as WebP or AVIF are usually much smaller at the same quality, and every current browser shows them.

1 image further down the page (73 KiB) download before anyone scrolls to it. Adding loading="lazy" lets the first screen load first.

By the Sustainable Web Design model, a visit to your homepage emits about 0.50 g of CO₂e: 60.3 kg a year at 10,000 visits a month. It scales with page weight, so every byte cut lowers it.

Images must have alternative text: 1 element on the page fails this check, rated critical by axe-core.

Scrollable region must have keyboard access: 1 element on the page fails this check, rated serious by axe-core.

All page content should be contained by landmarks: 3 elements on the page fail this check, rated moderate by axe-core.

Landmarks should have a unique role or role/label/title (i.e. accessible name) combination: 1 element on the page fails this check, rated moderate by axe-core.

The viewport tag blocks pinch-zoom, which low-vision visitors rely on.

1 visible link has no text or label, so screen readers cannot say where it goes.

Headings skip levels (h1 → h6 and h2 → h5), which makes the page harder to scan with a screen reader.

No meta description, so Google writes its own snippet from whatever text it finds.

Your title is only 15 characters: “Home - Madrigal”. Between 30 and 65 characters leaves room to say what you do and for whom.

The homepage links to 28 pages on madrigalpharma.com and 18 external pages.

There is no https://www.madrigalpharma.com/llms.txt, a short Markdown guide to your key pages for AI tools (llmstxt.org). It is optional and few AI tools read it yet, so treat it as a cheap extra.

https://www.madrigalpharma.com/contact-us, https://www.madrigalpharma.com/about, https://www.madrigalpharma.com/about/our-leaders, https://www.madrigalpharma.com/about/community, https://www.madrigalpharma.com/therapeutic-focus and https://www.madrigalpharma.com/therapeutic-focus/what-is-mash and 8 others have no meta description, so Google writes the search snippet from whatever text it finds.

We fetched 14 pages linked from your homepage and read each the way a search engine does.

9 of 23 tappable elements near the top of the page are smaller than 24 px, hard to hit with a thumb.

No testimonials, customer logos, ratings or customer counts on the homepage: nothing tells a new visitor that others already trust you.

No phone number or email link on the homepage, so ready-to-buy visitors have one fewer way to reach you.

No guarantee or risk reducer (money-back, free trial, no credit card) is mentioned, which is often what tips a hesitant visitor.

The homepage carries about 525 words of visible text.

Before a visitor clicks anything, the page loads Google Analytics and Google Tag Manager (measured from a US location before any click). A consent tool (Usercentrics) is installed; check it blocks these until visitors agree where the law requires it.

Opening the homepage sets 3 cookies (measured from a US location before any click).

Loading the homepage contacts 11 hosts run by other companies (fonts, scripts, analytics, ads), each of which sees the visitor's IP address.