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  • This week · 6
  • This quarter · 9
  • Big bets · 4
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Generated Oct 23, 2026
  1. Programmable
  2. Playbooks
  3. Chai Discovery
Chai Discovery logo

growth playbook · Oct 23, 2026

chaidiscovery.com (opens in a new tab)

Chai Discovery growth playbook

Diagnosis

Chai Discovery has rare momentum: six pharma partners in nine months, $400M raised at a $3.8B valuation, and a GSK evaluation that found binders to every tested target. It is now making its first marketing hire, building a partnerships team (BD, engagement management, forward-deployed scientists) and a strategy team asking how to price and which segments to enter.

The website has not caught up: every page shares one title and description, the sitemap omits all 11 posts, the Platform page still sells Chai-2, the homepage misses GSK and BMS, and the main claims are split into single letters.

This playbook fixes those first, then packages the wet-lab evaluation, builds a results page, plans JPM, adds partner stories and a TuneLab path, and longer-term sets pricing by segment, API access, an open design challenge and a residency.

Growth Score

8/10

Biggest Opportunity

Turn each partner result into the next deal: a repeatable evaluation offer, measured results in one place, and announcements that travel with their own headlines.

Biggest Risk

Pharma partners build their own models and other AI design companies compete for the same programs; if results are not visible and verifiable, Chai's lead becomes harder to prove.

01

Start here

The three moves to make first. Each one is written up in full below.

  1. 1

    Every Chai page, even the $400M Series C, shares one title and description

    Write titles and descriptions for the five most recent posts today.

    High impact First result in 1 week
  2. 2

    Put Chai-3 on the Platform page; it still sells Chai-2

    Fix the three typos and add one Chai-3 line today.

    High impact First result in 2 weeks
  3. 3

    Show all six pharma partners on the homepage

    Add GSK and Bristol Myers Squibb to the strip.

    Medium impact First result in 1 week

02

Your idea portfolio

21 ideas, grouped by when to run them. Open any idea for how to run it: the steps, who to approach, copy you can use, and how to measure it.

  • 6 ideas are marked Unexpected: plays you are unlikely to have tried.

    1 of these are things Programmable can build and run for you.

Every idea placed by the effort it takes against the impact it could have. Quick wins sit top left; select a number to open that idea. The filters below narrow the list by status, timing, category and what Programmable can build.

Effort vs impactEach number is an idea. Select one to open it.
Impact →
Quick wins · 2Big bets · 10Fill-ins · 7Reconsider · 2
Effort →

Showing 21 of 21 ideas

This week 6

Quick wins with a clear first action.

  • 01

    Chai is hiring its first marketing lead to shape "how we show up online". Today every page has the same title ("Chai Discovery"), the same description and the same social title, from the Series C to the GSK and Chai-2 posts. When a pharma executive or engineer shares the GSK news on LinkedIn, the preview says "Chai Discovery: Building frontier artificial intelligence..." rather than the deal. The sitemap lists 6 URLs and none of the 11 company posts.

    High impactLow effort First result in 1 week Brand and Marketing lead

    First action

    Write titles and descriptions for the five most recent posts today.

    How to measure it

    Pages with unique metadata

    Now
    –
    Target
    100%
    By
    2 weeks

    Steps

    1. 1

      List pages

      All 17 pages and posts.

      Brand and Marketing lead 1 hour

    2. 2

      Write metadata

      Title, description and share image per page.

      Brand and Marketing lead 1 day

    3. 3

      Apply in Framer

      Page settings for each.

      Design Engineer 1 day

    4. 4

      Fix the sitemap

      Include every post.

      Design Engineer 1 hour

    5. 5

      Add schema

      Article with date and author.

      Design Engineer 1 day

    6. 6

      Check previews

      LinkedIn Post Inspector and X card check.

      Brand and Marketing lead 1 hour

    7. 7

      Make it a rule

      Checklist for each announcement.

      Brand and Marketing lead ongoing

    First result
    1 week
    Cost
    $0
    Owner
    Brand and Marketing lead

    Smallest test

    Fix the GSK post's title and description and re-share it.

    Why it works

    Give each page and post its own title, description and share image (for example "Chai Discovery and GSK collaborate after wet-lab evaluation"), add Article schema with dates, and turn on the full sitemap so every post is listed. Make "title, description, image" part of the publishing checklist for every future announcement, starting before JPM.

    Each announcement then travels with its own headline in previews, search results and AI answers. It is a one-day change in Framer settings, and it makes the next partnership land harder.

    Ready to use

    ChecklistAnnouncement publishing checklist

    [ ] Unique page title with the news
    [ ] Meta description: what, who, why it matters
    [ ] Share image with partner or model name
    [ ] Article schema with date
    [ ] Listed in sitemap
    [ ] Linked from Research & News and the homepage
    [ ] Preview checked on LinkedIn and X

    Risks and how to handle them

    • Old previews are cached

      Re-scrape the top posts in LinkedIn Post Inspector.

    Evidence

    • Your websitePage metadata (checked October 22, 2026): every page tested, including the homepage, Platform, Careers, the $400M Series C post and the GSK, Novartis, argenx and Chai-2 posts, has the same title "Chai Discovery", the same meta description ("Building frontier artificial intelligence to predict and reprogram the interactions between biochemical molecules.") and the same og:title. The sitemap lists 6 URLs (home, product, news, careers, terms, privacy); none of the 11 company posts linked from Research & News (seed, Series A, B and C, introducing Chai-1 and Chai-2, the Chai-2 antibody update, and the Novartis, argenx, BMS and GSK posts) is in it.Source
    • HiringBrand and Marketing (posted September 30, 2026): "our first marketing hire", to "refine and establish the Chai brand: How we show up online and off"; audiences "range from pharma executives and scientists to AI researchers and engineers"; "making key moments count at JPM, partner events, and the AI and science conferences"; "building platforms that give our founders and researchers more reach"; "making Chai more legible and compelling to the engineers and researchers we want to hire, including those with no background in biology"; "putting a playbook in place". "This role is not about demand gen or social media maxxing."Source
    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
  • 02

    Chai-3 is the model Pfizer licenses and the Series C credits with unlocking hard targets, but the Platform page still says "Learn more about the Chai-2 series" and "We are opening up access to Chai-2". No page introduces Chai-3. The page also has copy errors ("stuctures", "antigen confirmations", "such as like").

    High impactLow effort First result in 2 weeks Brand and Marketing lead

    First action

    Fix the three typos and add one Chai-3 line today.

    How to measure it

    Platform access requests

    Now
    –
    Target
    +30%
    By
    90 days

    Steps

    1. 1

      Agree claims

      What can be said about Chai-3.

      Research Scientist 2 days

    2. 2

      Rewrite

      Current model and results.

      Brand and Marketing lead 2 days

    3. 3

      Fix copy

      Typos and terms.

      Brand and Marketing lead 1 hour

    4. 4

      Design

      Model visuals.

      Design Engineer 2 days

    5. 5

      Publish post

      Short Chai-3 introduction.

      Brand and Marketing lead 1 week

    6. 6

      Measure

      Form starts and completions.

      Design Engineer monthly

    First result
    2 weeks
    Cost
    Staff time only
    Owner
    Brand and Marketing lead

    Smallest test

    Correct the typos and change the Chai-2 access line today.

    Why it works

    Rewrite the Platform page around the current model: what Chai-3 adds, the measured results (success rates, the GSK wet-lab evaluation, time to characterization), formats supported and how to get access. Publish a short Chai-3 post with whatever technical detail is public, and fix the typos.

    Pharma scientists checking the platform after a press story should find the model the press described, and accurate copy matters to a science audience.

    Risks and how to handle them

    • Revealing too much

      Share results partners have already made public.

    Evidence

    • Your websitePlatform page (/product): headline "De novo protein design that works reliably"; ">10%" success rates for antibodies and ">50%" for miniproteins; characterization "in <2 weeks"; "Learn more about the Chai-2 series of models"; "We are opening up access to Chai-2 to commercial organizations"; academic "limited non-commercial use"; one access form (name, email, organization, type, size, intended use). Chai-3 is not mentioned on the Platform page or the homepage, and no post introduces it. Copy errors on the page include "stuctures", "antigen confirmations" and "such as like".Source
    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
    • HiringBrand and Marketing (posted September 30, 2026): "our first marketing hire", to "refine and establish the Chai brand: How we show up online and off"; audiences "range from pharma executives and scientists to AI researchers and engineers"; "making key moments count at JPM, partner events, and the AI and science conferences"; "building platforms that give our founders and researchers more reach"; "making Chai more legible and compelling to the engineers and researchers we want to hire, including those with no background in biology"; "putting a playbook in place". "This role is not about demand gen or social media maxxing."Source
  • 03

    Endpoints called GSK Chai's "sixth pharma partner in nine months", and the job posts name Lilly, GSK, Pfizer, Bristol Myers, argenx and Novartis. The homepage partner strip shows four, missing the two newest: GSK and Bristol Myers Squibb.

    Medium impactLow effort First result in 1 week Brand and Marketing lead

    First action

    Add GSK and Bristol Myers Squibb to the strip.

    How to measure it

    News clicks from homepage

    Now
    –
    Target
    +25%
    By
    60 days

    Steps

    1. 1

      Get approvals

      Logo use per partner.

      Business Development lead 1 week

    2. 2

      Update strip

      Six partners.

      Design Engineer 1 day

    3. 3

      Add proof line

      Six partners in nine months.

      Brand and Marketing lead 1 hour

    4. 4

      Link posts

      Each partner to its post.

      Design Engineer 1 hour

    5. 5

      Set the rule

      Homepage on announcement day.

      Brand and Marketing lead ongoing

    6. 6

      Measure

      Clicks to news.

      Design Engineer monthly

    First result
    1 week
    Cost
    $0
    Owner
    Brand and Marketing lead

    Smallest test

    Add the two names in text today.

    Why it works

    Update the strip to all six with links to each announcement, add one line of proof ("six pharma partners in nine months"), and set a rule that every new partner goes on the homepage the day it is announced.

    Momentum is Chai's strongest message to the next partner and to candidates, and the homepage is the first place they look.

    Risks and how to handle them

    • Logo permissions

      Use names in text where logos are not approved.

    Evidence

    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • HiringSoftware Engineer, Developer & Research Platform (posted October 12, 2026): ships "the research platform where people and agents launch experiments, compare results, and decide what to try next". Every post describes Chai as "the computer-aided design suite for molecules" with "a computational workspace to iterate on molecules from idea to medicine", used by Eli Lilly, GSK, Pfizer, Bristol Myers, argenx and Novartis.Source
  • 04

    The Careers headline reads "Join and work one the most meaningful problems AI." The brand hire is asked to make Chai "legible and compelling to the engineers and researchers we want to hire, including those with no background in biology", and the strategy team names "winning the war for talent".

    Medium impactLow effort First result in 1 month Talent lead

    First action

    Correct the headline today.

    How to measure it

    Engineering applications

    Now
    –
    Target
    +30%
    By
    2 quarters

    Steps

    1. 1

      Fix the headline

      Today.

      Talent lead 10 minutes

    2. 2

      Draft the explainer

      Biology for engineers.

      Brand and Marketing lead 1 week

    3. 3

      Interview engineers

      Three short quotes.

      Talent lead 1 week

    4. 4

      Design

      Simple diagrams.

      Design Engineer 1 week

    5. 5

      Publish

      On Careers.

      Design Engineer 1 day

    6. 6

      Measure

      Applications by role.

      Talent lead monthly

    First result
    1 month
    Cost
    $0
    Owner
    Talent lead

    Smallest test

    Fix the headline today.

    Why it works

    Correct the headline, then add a page or section that explains Chai to an ML engineer: what a binder is, why design beats screening, what the models do, what engineers work on, and quotes from engineers who joined without biology backgrounds.

    Candidates apply when they understand the problem, and a clear explainer widens the pool beyond biology.

    Risks and how to handle them

    • Oversimplifying the science

      Have a scientist review it.

    Evidence

    • Your websiteHomepage and Careers: the two main homepage statements ("Chai powers drug discovery programs at the world's leading pharmaceutical companies." and the "Our models learn..." paragraph) are split into one element per letter with no accessible label, so text tools read "C h a i p o w e r s ...". The Careers headline reads "Join and work one the most meaningful problems AI." Contact is by email only (info@ and [email protected]).Source
    • HiringBrand and Marketing (posted September 30, 2026): "our first marketing hire", to "refine and establish the Chai brand: How we show up online and off"; audiences "range from pharma executives and scientists to AI researchers and engineers"; "making key moments count at JPM, partner events, and the AI and science conferences"; "building platforms that give our founders and researchers more reach"; "making Chai more legible and compelling to the engineers and researchers we want to hire, including those with no background in biology"; "putting a playbook in place". "This role is not about demand gen or social media maxxing."Source
    • HiringStrategy (posted September 30, 2026): "Chai's business model has no real precedent"; open questions include "how we price, which segments and products we expand into, and what makes our position durable", plus "scaling lab capacity" and "winning the war for talent". First Finance Hire (August 31): "pharmaceutical partnerships with complex revenue recognition" and "heavy spend on compute and data acquisition".Source
  • 05

    The Platform page has one form for everyone. Large pharma deals run through the partnerships team, biotechs can evaluate Chai through Lilly TuneLab, and academics wait for limited non-commercial access. Each needs a different next step.

    Medium impactLow effort First result in 2 weeks Business Development lead

    First action

    Count last quarter's form entries by type.

    How to measure it

    Pharma reply time

    Now
    –
    Target
    Under 1 business day
    By
    60 days

    Steps

    1. 1

      Count entries

      By type and size.

      Business Development lead 1 day

    2. 2

      Design routes

      Three paths.

      Business Development lead 2 days

    3. 3

      Update form

      Type first, next steps shown.

      Design Engineer 2 days

    4. 4

      Set alerts

      Pharma to BD immediately.

      Business Development lead 1 day

    5. 5

      Write replies

      Templates per path.

      Engagement Manager 2 days

    6. 6

      Measure

      Reply time and meetings.

      Business Development lead monthly

    First result
    2 weeks
    Cost
    $0
    Owner
    Business Development lead

    Smallest test

    Add the "what happens next" text to the form.

    Why it works

    Ask organization type first and route: pharma to a BD call with the evaluation offer, biotechs to the TuneLab path (and Chai's own option), academics to the research access waitlist. Tell each what happens next and when.

    Clear routes stop high-value pharma requests from waiting in a general inbox and give smaller groups a fast answer.

    Risks and how to handle them

    • More admin

      Automate the academic and biotech replies.

    Evidence

    • Your websitePlatform page (/product): headline "De novo protein design that works reliably"; ">10%" success rates for antibodies and ">50%" for miniproteins; characterization "in <2 weeks"; "Learn more about the Chai-2 series of models"; "We are opening up access to Chai-2 to commercial organizations"; academic "limited non-commercial use"; one access form (name, email, organization, type, size, intended use). Chai-3 is not mentioned on the Platform page or the homepage, and no post introduces it. Copy errors on the page include "stuctures", "antigen confirmations" and "such as like".Source
    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • HiringPartnerships founding team (posted March 2026, still open): Business Development to "set the terms and drive deal execution with the world's leading life sciences companies" ("Deal volume and demand are accelerating fast"); Engagement Management to keep partnerships healthy, "accelerating time to clinic", and to synthesize "actionable intelligence for the rest of the company"; Forward-Deployed Scientists to act as "a power user" and "advisor to some of the most important drug programs of our time".Source
  • 06

    The two main homepage statements are animated letter by letter, and in the HTML each letter is its own element with no accessible label, so text tools read "C h a i p o w e r s d r u g ...". The core claim about leading pharma companies is the sentence most likely to be read by assistive tech, search and AI systems.

    Medium impactLow effort First result in 1 week Design Engineer

    First action

    Add an aria-label to the first animated sentence.

    How to measure it

    Lighthouse accessibility

    Now
    –
    Target
    95
    By
    1 month

    Steps

    1. 1

      Find blocks

      All per-letter animations.

      Design Engineer 1 hour

    2. 2

      Add labels

      Full sentence per block.

      Design Engineer 2 hours

    3. 3

      Hide letters

      From assistive tech.

      Design Engineer 1 hour

    4. 4

      Test

      VoiceOver and text fetch.

      Design Engineer 1 hour

    5. 5

      Fix others

      Button names, contrast, landmarks.

      Design Engineer 1 day

    6. 6

      Recheck

      Lighthouse.

      Design Engineer 1 hour

    First result
    1 week
    Cost
    $0
    Owner
    Design Engineer

    Smallest test

    Label one sentence and test with VoiceOver.

    Why it works

    Add an accessible label with the full sentence to each animated block (and hide the letter elements from assistive tech), or keep the animation on a visual layer over real text. Test with VoiceOver and a text-only fetch.

    The homepage claim then reads as a sentence everywhere, at no cost to the design.

    Risks and how to handle them

    • Animation breaks

      Test on mobile and desktop.

    Evidence

    • Your websiteHomepage and Careers: the two main homepage statements ("Chai powers drug discovery programs at the world's leading pharmaceutical companies." and the "Our models learn..." paragraph) are split into one element per letter with no accessible label, so text tools read "C h a i p o w e r s ...". The Careers headline reads "Join and work one the most meaningful problems AI." Contact is by email only (info@ and [email protected]).Source
    • Google PageSpeedHomepage: real Chrome visitors pass Core Web Vitals (LCP 2.5 s, INP 138 ms, CLS 0 at the 75th percentile). In the mobile lab test the score is 35 (desktop 33) and the largest element appears at 13.6 s; 1.26 MB of the 1.9 MB page is a 3D molecule viewer library loaded from a public CDN on every page, with 7.6 s of render-blocking requests, 945 KB of unused JavaScript and five accessibility issues.Source

This quarter 9

The core plays for the next three months.

  • 07

    GSK expanded into a broader collaboration after an evaluation in which Chai's zero-shot designs produced binders to all tested targets in GSK's own lab. Chai's BD team says deal volume is accelerating, and pharma buyers want empirical proof.

    High impactMedium effort First result in 1 quarter Business Development lead

    First action

    Write a one-page evaluation term sheet.

    How to measure it

    Pharma evaluations

    Now
    –
    Target
    4
    By
    2 quarters

    Steps

    1. 1

      Define scope

      Targets, timeline, deliverables.

      Business Development lead 2 weeks

    2. 2

      Price it

      Fee or credit toward a deal.

      Strategy lead 2 weeks

    3. 3

      Write the page

      With the GSK example.

      Brand and Marketing lead 1 week

    4. 4

      Staff it

      Forward-deployed scientists per evaluation.

      Forward-Deployed Scientist ongoing

    5. 5

      Run

      Per partner.

      Engagement Manager 1 quarter

    6. 6

      Convert

      Results to collaboration terms.

      Business Development lead per evaluation

    First result
    1 quarter
    Cost
    Scientist time
    Owner
    Business Development lead

    Smallest test

    Offer the evaluation to two pharma prospects.

    Why it works

    Publish an "evaluation program" page: a fixed scope (a set number of targets chosen by the partner), timelines, what the partner tests in its own lab, how results lead to a collaboration, and the GSK outcome as the example. Use it as the opening offer in every BD conversation.

    A standard evaluation lowers the first commitment and turns Chai's results into each buyer's own data.

    Risks and how to handle them

    • Weak results on hard targets

      Agree target selection and success criteria up front.

    Evidence

    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
    • HiringPartnerships founding team (posted March 2026, still open): Business Development to "set the terms and drive deal execution with the world's leading life sciences companies" ("Deal volume and demand are accelerating fast"); Engagement Management to keep partnerships healthy, "accelerating time to clinic", and to synthesize "actionable intelligence for the rest of the company"; Forward-Deployed Scientists to act as "a power user" and "advisor to some of the most important drug programs of our time".Source
    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
  • 08

    Chai's proof is spread across posts: Chai-2's double-digit hit rates, 50% of 52 targets with binders, >10% for antibodies, >50% for miniproteins, binders to all GSK targets tested. Pharma scientists and AI researchers want one place to see what each model achieves.

    High impactMedium effort First result in 1 quarter Research Scientist

    First action

    Collect every published number into one table.

    How to measure it

    Monthly visits

    Now
    –
    Target
    5,000
    By
    2 quarters

    Steps

    1. 1

      Collect numbers

      All public results.

      Research Scientist 1 week

    2. 2

      Design the page

      Table by model.

      Design Engineer 1 week

    3. 3

      Review

      Accuracy and wording.

      Research Scientist 1 week

    4. 4

      Publish

      With dates and links.

      Brand and Marketing lead 1 day

    5. 5

      Update

      Each release.

      Research Scientist per release

    6. 6

      Promote

      Researcher networks.

      Brand and Marketing lead ongoing

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    Research Scientist

    Smallest test

    Publish the table for Chai-2.

    Why it works

    Publish a living results page: per model (Chai-1, Chai-2, Chai-3), the benchmarks, wet-lab results, formats and dates, with links to technical reports. Update it with each release.

    A single source of measured results is what scientists cite and what AI assistants quote.

    Risks and how to handle them

    • Numbers taken out of context

      State the setup next to each figure.

    Evidence

    • Your websiteIntroducing Chai-2 (June 30, 2025): "double digit hit rates in de novo antibody design"; "When testing just 20 designs, the model routinely discovers viable hits"; 52 novel antigens targeted, with successful binders for 50% of tested targets; a technical report PDF.Source
    • Your websitePlatform page (/product): headline "De novo protein design that works reliably"; ">10%" success rates for antibodies and ">50%" for miniproteins; characterization "in <2 weeks"; "Learn more about the Chai-2 series of models"; "We are opening up access to Chai-2 to commercial organizations"; academic "limited non-commercial use"; one access form (name, email, organization, type, size, intended use). Chai-3 is not mentioned on the Platform page or the homepage, and no post introduces it. Copy errors on the page include "stuctures", "antigen confirmations" and "such as like".Source
    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
    • GitHubchai-lab, the open-source Chai-1 repository ("SOTA model for biomolecular structure prediction", Apache-2.0), has 2,004 stars and 295 forks; last push June 30, 2026. The Chai-1 launch reached 270 points on Hacker News.Source
  • 09

    The brand hire is asked to make "key moments count at JPM". With six pharma partners in nine months, Chai arrives at the January conference with momentum and a crowded calendar of pharma executives.

    High impactMedium effort First result in JPM week Brand and Marketing lead

    First action

    List the 30 executives Chai most wants to meet at JPM.

    How to measure it

    JPM meetings with target pharma

    Now
    –
    Target
    25
    By
    JPM week

    Steps

    1. 1

      Target list

      30 executives.

      Business Development lead 1 week

    2. 2

      Book venues

      Briefing and dinners.

      Brand and Marketing lead 2 weeks

    3. 3

      Invite

      Founder-signed invitations.

      Co-founder and CEO 3 weeks

    4. 4

      Prepare content

      Briefing deck and results.

      Forward-Deployed Scientist 1 month

    5. 5

      Announce

      One timed release.

      Brand and Marketing lead JPM week

    6. 6

      Follow up

      Within a week.

      Business Development lead 1 week

    First result
    JPM week
    Cost
    Event costs
    Owner
    Brand and Marketing lead

    Smallest test

    Send the first ten invitations.

    Build the prospect list. The list compiled from public sources, verified, deduplicated and delivered to your CRM. Usually live within days.

    Book a working session

    Why it works

    Plan JPM week now: a small technical briefing for heads of discovery, two partner dinners, founder meetings booked ahead with target pharma companies, and one announcement timed for the week with its own page and share image.

    The right executives are in one city for a few days, and a planned week turns that into pipeline.

    Risks and how to handle them

    • Calendar crowded

      Book meetings weeks ahead.

    Evidence

    • HiringBrand and Marketing (posted September 30, 2026): "our first marketing hire", to "refine and establish the Chai brand: How we show up online and off"; audiences "range from pharma executives and scientists to AI researchers and engineers"; "making key moments count at JPM, partner events, and the AI and science conferences"; "building platforms that give our founders and researchers more reach"; "making Chai more legible and compelling to the engineers and researchers we want to hire, including those with no background in biology"; "putting a playbook in place". "This role is not about demand gen or social media maxxing."Source
    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • HiringPartnerships founding team (posted March 2026, still open): Business Development to "set the terms and drive deal execution with the world's leading life sciences companies" ("Deal volume and demand are accelerating fast"); Engagement Management to keep partnerships healthy, "accelerating time to clinic", and to synthesize "actionable intelligence for the rest of the company"; Forward-Deployed Scientists to act as "a power user" and "advisor to some of the most important drug programs of our time".Source
  • 10

    Partners are adopting Chai "across their organizations", and Lilly's TuneLab passed 100 members after adding Chai models. The site has announcements but no account of what partner scientists actually did with the platform.

    High impactMedium effort First result in 2 quarters Engagement Manager

    First action

    Ask two partner scientists to co-present at a conference.

    How to measure it

    Stories or talks

    Now
    –
    Target
    4
    By
    2 quarters

    Steps

    1. 1

      Pick partners

      Those open to speaking.

      Engagement Manager 2 weeks

    2. 2

      Agree scope

      What can be shared.

      Business Development lead 1 month

    3. 3

      Interview

      Partner scientists.

      Forward-Deployed Scientist 2 weeks

    4. 4

      Write or present

      Story or talk.

      Brand and Marketing lead 1 month

    5. 5

      Approve

      Partner review.

      Engagement Manager 1 month

    6. 6

      Publish

      Site and conferences.

      Brand and Marketing lead per story

    First result
    2 quarters
    Cost
    Staff time only
    Owner
    Engagement Manager

    Smallest test

    Propose one co-presented talk.

    Why it works

    With partner approval, publish short stories or co-authored talks: the problem, how the team used Chai, what changed in their workflow. Start with partners that already speak publicly (Lilly TuneLab, GSK's evaluation quotes).

    Peer scientists trust peer stories more than company claims, and partners gain visibility for their own teams.

    Risks and how to handle them

    • Pharma confidentiality

      Focus on workflow, not targets.

    Evidence

    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
    • HiringPartnerships founding team (posted March 2026, still open): Business Development to "set the terms and drive deal execution with the world's leading life sciences companies" ("Deal volume and demand are accelerating fast"); Engagement Management to keep partnerships healthy, "accelerating time to clinic", and to synthesize "actionable intelligence for the rest of the company"; Forward-Deployed Scientists to act as "a power user" and "advisor to some of the most important drug programs of our time".Source
  • 11

    The brand role exists partly to build "platforms that give our founders and researchers more reach". The Research & News feed is mostly press coverage and deal releases; the last research post was the Chai-2 antibody update in November 2025.

    Medium impactMedium effort First result in 2 quarters Brand and Marketing lead

    First action

    Pick the first three researcher posts.

    How to measure it

    Posts and talks per quarter

    Now
    –
    Target
    6
    By
    2 quarters

    Steps

    1. 1

      Plan topics

      Quarter ahead.

      Brand and Marketing lead 1 week

    2. 2

      Support writing

      Editing help.

      Brand and Marketing lead monthly

    3. 3

      Review

      Confidentiality check.

      Research Scientist monthly

    4. 4

      Publish

      With unique metadata.

      Brand and Marketing lead monthly

    5. 5

      Submit talks

      Conferences.

      Brand and Marketing lead quarterly

    6. 6

      Measure

      Reads and citations.

      Brand and Marketing lead quarterly

    First result
    2 quarters
    Cost
    Staff time only
    Owner
    Brand and Marketing lead

    Smallest test

    Publish one researcher post this month.

    Why it works

    Publish one technical post a month by a researcher (methods, lessons, failures worth sharing), give each a talk version for AI and science conferences, and track speaking slots and citations.

    Researchers are the brand for both scientists and recruits, and regular technical writing compounds.

    Risks and how to handle them

    • Research time lost

      Keep posts short and edited by marketing.

    Evidence

    • HiringBrand and Marketing (posted September 30, 2026): "our first marketing hire", to "refine and establish the Chai brand: How we show up online and off"; audiences "range from pharma executives and scientists to AI researchers and engineers"; "making key moments count at JPM, partner events, and the AI and science conferences"; "building platforms that give our founders and researchers more reach"; "making Chai more legible and compelling to the engineers and researchers we want to hire, including those with no background in biology"; "putting a playbook in place". "This role is not about demand gen or social media maxxing."Source
    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • Your websiteIntroducing Chai-2 (June 30, 2025): "double digit hit rates in de novo antibody design"; "When testing just 20 designs, the model routinely discovers viable hits"; 52 novel antigens targeted, with successful binders for 50% of tested targets; a technical report PDF.Source
  • 12

    Lilly's TuneLab gives select biotechs access to Chai's miniprotein design suite, its first outside models, and passed 100 members. Those biotechs are future direct customers, but chaidiscovery.com has no page for them.

    High impactMedium effort First result in 2 quarters Business Development lead

    First action

    Ask Lilly what co-marketing is allowed.

    How to measure it

    Direct-access requests from TuneLab users

    Now
    –
    Target
    10
    By
    2 quarters

    Steps

    1. 1

      Agree with Lilly

      Co-marketing terms.

      Business Development lead 1 month

    2. 2

      Write the page

      For TuneLab biotechs.

      Brand and Marketing lead 1 week

    3. 3

      Add guides

      Getting started.

      Forward-Deployed Scientist 2 weeks

    4. 4

      Route requests

      To BD.

      Business Development lead 1 day

    5. 5

      Host sessions

      Office hours.

      Forward-Deployed Scientist monthly

    6. 6

      Measure

      Requests and deals.

      Business Development lead quarterly

    First result
    2 quarters
    Cost
    Staff time only
    Owner
    Business Development lead

    Smallest test

    Publish a short TuneLab FAQ.

    Why it works

    Publish a TuneLab page: what biotechs can try, how to get the most from it, and how to work with Chai directly as they grow. Track which TuneLab users ask for direct access.

    A partner channel already reaches more than 100 biotechs; a clear next step turns users into customers.

    Risks and how to handle them

    • Partner conflict

      Keep Lilly informed and aligned.

    Evidence

    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • Your websitePlatform page (/product): headline "De novo protein design that works reliably"; ">10%" success rates for antibodies and ">50%" for miniproteins; characterization "in <2 weeks"; "Learn more about the Chai-2 series of models"; "We are opening up access to Chai-2 to commercial organizations"; academic "limited non-commercial use"; one access form (name, email, organization, type, size, intended use). Chai-3 is not mentioned on the Platform page or the homepage, and no post introduces it. Copy errors on the page include "stuctures", "antigen confirmations" and "such as like".Source
  • 13

    chai-lab has 2,004 stars and 295 forks, and the last push was June 2026. Many of those users are computational biologists at biotechs and universities, the same people who later evaluate Chai-2 and Chai-3, but the repository and the site do not connect.

    Medium impactLow effort First result in 1 quarter Software Engineer

    First action

    Add a Platform link and a short next-step section to the README.

    How to measure it

    Requests from Chai-1 users

    Now
    –
    Target
    20 a quarter
    By
    2 quarters

    Steps

    1. 1

      Update README

      Links and next steps.

      Software Engineer, Developer & Research Platform 1 day

    2. 2

      Release notes

      Each update.

      Software Engineer, Developer & Research Platform per release

    3. 3

      Add tracking

      Source on the form.

      Design Engineer 1 day

    4. 4

      Office hours

      Monthly.

      Forward-Deployed Scientist monthly

    5. 5

      Invite users

      Active contributors.

      Business Development lead quarterly

    6. 6

      Measure

      Requests from GitHub.

      Business Development lead quarterly

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    Software Engineer, Developer & Research Platform

    Smallest test

    Update the README this week.

    Why it works

    Link the repository to the Platform page and the results page, add a "what's next after Chai-1" section, publish release notes, and invite active users to research access and office hours.

    Open-source users are already qualified and can become champions inside their companies.

    Risks and how to handle them

    • Support load

      Keep office hours and issues triaged.

    Evidence

    • GitHubchai-lab, the open-source Chai-1 repository ("SOTA model for biomolecular structure prediction", Apache-2.0), has 2,004 stars and 295 forks; last push June 30, 2026. The Chai-1 launch reached 270 points on Hacker News.Source
    • Your websitePlatform page (/product): headline "De novo protein design that works reliably"; ">10%" success rates for antibodies and ">50%" for miniproteins; characterization "in <2 weeks"; "Learn more about the Chai-2 series of models"; "We are opening up access to Chai-2 to commercial organizations"; academic "limited non-commercial use"; one access form (name, email, organization, type, size, intended use). Chai-3 is not mentioned on the Platform page or the homepage, and no post introduces it. Copy errors on the page include "stuctures", "antigen confirmations" and "such as like".Source
  • 14

    The Platform page promises Chai-2 for "limited non-commercial use" with an early-access form. Academic labs publish, and each paper using Chai is proof and a citation.

    Medium impactMedium effort First result in 2 quarters Research Scientist

    First action

    Pick the first five labs.

    How to measure it

    Publications

    Now
    –
    Target
    10
    By
    1 year

    Steps

    1. 1

      Set rules

      Capacity and terms.

      Research Scientist 2 weeks

    2. 2

      Open call

      Proposals.

      Brand and Marketing lead 2 weeks

    3. 3

      Select labs

      Five per quarter.

      Research Scientist quarterly

    4. 4

      Support

      Office hours.

      Forward-Deployed Scientist monthly

    5. 5

      Feature work

      On the site.

      Brand and Marketing lead per paper

    6. 6

      Review

      Program value.

      Strategy lead quarterly

    First result
    2 quarters
    Cost
    Compute credits
    Owner
    Research Scientist

    Smallest test

    Admit three labs.

    Why it works

    Launch a selective academic program: a set number of labs per quarter, a short proposal, credits and a request to cite and share results. Highlight published work on the site.

    Academic papers build scientific credibility with pharma and attract research talent.

    Risks and how to handle them

    • Compute cost

      Cap credits per lab.

    Evidence

    • Your websitePlatform page (/product): headline "De novo protein design that works reliably"; ">10%" success rates for antibodies and ">50%" for miniproteins; characterization "in <2 weeks"; "Learn more about the Chai-2 series of models"; "We are opening up access to Chai-2 to commercial organizations"; academic "limited non-commercial use"; one access form (name, email, organization, type, size, intended use). Chai-3 is not mentioned on the Platform page or the homepage, and no post introduces it. Copy errors on the page include "stuctures", "antigen confirmations" and "such as like".Source
    • Your websiteIntroducing Chai-2 (June 30, 2025): "double digit hit rates in de novo antibody design"; "When testing just 20 designs, the model routinely discovers viable hits"; 52 novel antigens targeted, with successful binders for 50% of tested targets; a technical report PDF.Source
  • 15

    Partners "have started adopting our models across their organizations", and engagement managers are measured on partnership health and growth. Adoption in big pharma spreads team by team.

    High impactMedium effort First result in 2 quarters Engagement Manager

    First action

    Count active teams at each partner today.

    How to measure it

    Teams using Chai per partner

    Now
    –
    Target
    2x
    By
    3 quarters

    Steps

    1. 1

      Count teams

      Per partner.

      Engagement Manager 1 week

    2. 2

      Find champions

      First successful teams.

      Engagement Manager 2 weeks

    3. 3

      Run workshops

      Internal sessions.

      Forward-Deployed Scientist monthly

    4. 4

      Report usage

      Quarterly reviews.

      Engagement Manager quarterly

    5. 5

      Plan expansion

      Next therapeutic areas.

      Business Development lead quarterly

    6. 6

      Feed product

      Requests to research.

      Engagement Manager monthly

    First result
    2 quarters
    Cost
    Scientist time
    Owner
    Engagement Manager

    Smallest test

    Run one workshop at one partner.

    Why it works

    In each partner, find the first successful team, run internal workshops with them for other therapeutic areas, share usage and results reports, and track the number of active teams per partner.

    More teams using Chai means larger renewals and a stronger position against in-house models.

    Risks and how to handle them

    • Competing internal models

      Show combined results, as GSK describes.

    Evidence

    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
    • HiringPartnerships founding team (posted March 2026, still open): Business Development to "set the terms and drive deal execution with the world's leading life sciences companies" ("Deal volume and demand are accelerating fast"); Engagement Management to keep partnerships healthy, "accelerating time to clinic", and to synthesize "actionable intelligence for the rest of the company"; Forward-Deployed Scientists to act as "a power user" and "advisor to some of the most important drug programs of our time".Source

Big bets 4

Larger plays that can change the trajectory.

  • 16

    The strategy team's first question is "how we price", for a business "with no real precedent", while finance handles "complex revenue recognition". Chai already serves pharma directly, biotechs through TuneLab and academics through early access.

    High impactHigh effort First result in 3 quarters Strategy lead

    First action

    Interview ten biotechs on how they would buy.

    How to measure it

    Paying biotechs

    Now
    –
    Target
    15
    By
    3 quarters

    Steps

    1. 1

      Research

      Interviews and comparables.

      Strategy lead 1 month

    2. 2

      Model

      Revenue and compute cost.

      First Finance Hire 1 month

    3. 3

      Design offers

      Three segments.

      Strategy lead 1 month

    4. 4

      Pilot

      Five biotechs.

      Business Development lead 1 quarter

    5. 5

      Decide

      Publish or adjust.

      Co-founder and CEO 1 month

    6. 6

      Review

      Twice a year.

      Strategy lead 6 months

    First result
    3 quarters
    Cost
    Strategy time
    Owner
    Strategy lead

    Smallest test

    Interview five biotechs this month.

    Why it works

    Interview partners and biotechs, then define three offers: enterprise collaborations, a biotech plan with usage-based access, and academic credits. Test the biotech plan with a few companies before publishing.

    A clear structure widens the market while keeping large deals bespoke.

    Risks and how to handle them

    • Underpricing

      Pilot before publishing.

    Evidence

    • HiringStrategy (posted September 30, 2026): "Chai's business model has no real precedent"; open questions include "how we price, which segments and products we expand into, and what makes our position durable", plus "scaling lab capacity" and "winning the war for talent". First Finance Hire (August 31): "pharmaceutical partnerships with complex revenue recognition" and "heavy spend on compute and data acquisition".Source
    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • Your websitePlatform page (/product): headline "De novo protein design that works reliably"; ">10%" success rates for antibodies and ">50%" for miniproteins; characterization "in <2 weeks"; "Learn more about the Chai-2 series of models"; "We are opening up access to Chai-2 to commercial organizations"; academic "limited non-commercial use"; one access form (name, email, organization, type, size, intended use). Chai-3 is not mentioned on the Platform page or the homepage, and no post introduces it. Copy errors on the page include "stuctures", "antigen confirmations" and "such as like".Source
  • 17

    Chai is building a research platform "where people and agents launch experiments" internally. Pharma computational teams want to run Chai models inside their own pipelines and agents.

    High impactHigh effort First result in 4 quarters Software Engineer

    First action

    Ask three partners how they would integrate.

    How to measure it

    API partners

    Now
    –
    Target
    3
    By
    4 quarters

    Steps

    1. 1

      Interview partners

      Integration needs.

      Forward-Deployed Scientist 1 month

    2. 2

      Design API

      Core endpoints.

      Software Engineer, Developer & Research Platform 1 quarter

    3. 3

      Security review

      Data handling.

      Software Engineer, Developer & Research Platform 1 month

    4. 4

      Pilot

      Two partners.

      Engagement Manager 1 quarter

    5. 5

      Document

      Developer overview.

      Software Engineer, Developer & Research Platform 1 month

    6. 6

      Scale

      All partners.

      Software Engineer, Developer & Research Platform 1 quarter

    First result
    4 quarters
    Cost
    Engineering time
    Owner
    Software Engineer, Developer & Research Platform

    Smallest test

    Prototype one endpoint with one partner.

    Why it works

    Offer partners a documented API and agent interface to the design suite, with usage reporting, and publish a public overview page for developers.

    Deeper integration raises usage and switching costs and suits partners' own automation.

    Risks and how to handle them

    • Data security concerns

      Point to the trust center and offer private deployment.

    Evidence

    • HiringSoftware Engineer, Developer & Research Platform (posted October 12, 2026): ships "the research platform where people and agents launch experiments, compare results, and decide what to try next". Every post describes Chai as "the computer-aided design suite for molecules" with "a computational workspace to iterate on molecules from idea to medicine", used by Eli Lilly, GSK, Pfizer, Bristol Myers, argenx and Novartis.Source
    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
  • 18

    Chai's message is that design now works "zero-shot", and GSK found binders to all tested targets. A public challenge on hard targets would show this to the whole field.

    High impactHigh effort First result in 4 quarters Co founder and CEO

    First action

    Choose five hard targets and a lab partner.

    How to measure it

    Teams entered

    Now
    –
    Target
    30
    By
    4 quarters

    Steps

    1. 1

      Pick targets

      Five hard targets.

      Research Scientist 1 month

    2. 2

      Lab partner

      Independent validation.

      Business Development lead 1 month

    3. 3

      Rules

      Open and fair.

      Research Scientist 1 month

    4. 4

      Run

      Design and test.

      Forward-Deployed Scientist 2 quarters

    5. 5

      Publish

      Results and data.

      Brand and Marketing lead 1 month

    6. 6

      Present

      Conference.

      Co-founder and CEO once

    First result
    4 quarters
    Cost
    Lab costs
    Owner
    Co founder and CEO

    Smallest test

    Agree targets with one lab.

    Why it works

    Run an open challenge: published targets, designs from Chai and invited teams, lab validation by an independent partner, and results published openly. Present at a major conference.

    Open, verified results earn scientific attention that no announcement can buy, and attract talent.

    Risks and how to handle them

    • Chai underperforms

      Report honestly; the field values it.

    Evidence

    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source
    • Your websiteIntroducing Chai-2 (June 30, 2025): "double digit hit rates in de novo antibody design"; "When testing just 20 designs, the model routinely discovers viable hits"; 52 novel antigens targeted, with successful binders for 50% of tested targets; a technical report PDF.Source
    • Competitor researchOthers in AI drug design, from their own homepages: Isomorphic Labs ("Reimagining Drug Discovery Process with AI"), Generate:Biomedicines ("a new kind of therapeutics company"), Nabla Bio and Latent Labs. Several develop their own drugs, while Chai positions itself as the design suite pharma licenses.Source
  • 19

    Chai hires "Outliers & Polymaths" and wants engineers "with no background in biology". A short residency would turn curious AI engineers into recruits.

    High impactMedium effort First result in 3 quarters Talent lead

    First action

    Design the first cohort of four.

    How to measure it

    Residents hired

    Now
    –
    Target
    50%
    By
    3 quarters

    Steps

    1. 1

      Design

      Projects and mentors.

      Talent lead 1 month

    2. 2

      Announce

      AI communities.

      Brand and Marketing lead 2 weeks

    3. 3

      Select

      Four residents.

      Talent lead 1 month

    4. 4

      Run

      12 weeks.

      Research Scientist 1 quarter

    5. 5

      Publish

      Projects.

      Brand and Marketing lead 2 weeks

    6. 6

      Offer

      Best residents.

      Talent lead 2 weeks

    First result
    3 quarters
    Cost
    Resident pay
    Owner
    Talent lead

    Smallest test

    Host one resident.

    Why it works

    Run a paid residency: a cohort of engineers works on real problems for 12 weeks with scientists, with offers for the best. Publish their projects.

    It builds a pipeline of trained hires and a story that makes Chai legible to the AI community.

    Risks and how to handle them

    • Mentor load

      Small cohorts.

    Evidence

    • HiringBrand and Marketing (posted September 30, 2026): "our first marketing hire", to "refine and establish the Chai brand: How we show up online and off"; audiences "range from pharma executives and scientists to AI researchers and engineers"; "making key moments count at JPM, partner events, and the AI and science conferences"; "building platforms that give our founders and researchers more reach"; "making Chai more legible and compelling to the engineers and researchers we want to hire, including those with no background in biology"; "putting a playbook in place". "This role is not about demand gen or social media maxxing."Source
    • Your websiteHomepage and Careers: the two main homepage statements ("Chai powers drug discovery programs at the world's leading pharmaceutical companies." and the "Our models learn..." paragraph) are split into one element per letter with no accessible label, so text tools read "C h a i p o w e r s ...". The Careers headline reads "Join and work one the most meaningful problems AI." Contact is by email only (info@ and [email protected]).Source
    • HiringStrategy (posted September 30, 2026): "Chai's business model has no real precedent"; open questions include "how we price, which segments and products we expand into, and what makes our position durable", plus "scaling lab capacity" and "winning the war for talent". First Finance Hire (August 31): "pharmaceutical partnerships with complex revenue recognition" and "heavy spend on compute and data acquisition".Source

Wildcards 2

Unexpected experiments, each with a cheap way to test it.

  • 20

    Real Chrome visitors pass Core Web Vitals, but in Google's phone lab test the homepage scores 35 and its largest element appears at 13.6 s. A 1.26 MB molecule viewer library from a public CDN loads on every page, with 7.6 s of render-blocking requests.

    Medium impactLow effort First result in 2 weeks Design Engineer

    First action

    Find which pages use the viewer.

    How to measure it

    Mobile performance score

    Now
    –
    Target
    70
    By
    1 quarter

    Steps

    1. 1

      Map use

      Pages with 3D models.

      Design Engineer 1 day

    2. 2

      Scope loading

      Only those pages.

      Design Engineer 2 days

    3. 3

      Defer

      Until visible.

      Design Engineer 1 day

    4. 4

      Remove extras

      Unused CSS.

      Design Engineer 1 hour

    5. 5

      Retest

      PageSpeed.

      Design Engineer 1 hour

    6. 6

      Monitor

      Monthly.

      Design Engineer monthly

    First result
    2 weeks
    Cost
    $0
    Owner
    Design Engineer

    Smallest test

    Remove the viewer from Careers and test.

    Why it works

    Load the viewer only on pages with a 3D structure, defer it until visible, and remove its stylesheet elsewhere. Retest in PageSpeed.

    Faster first views help executives opening news links on phones and improve how the site is crawled.

    Risks and how to handle them

    • Viewer breaks

      Test each page with a model.

    Evidence

    • Google PageSpeedHomepage: real Chrome visitors pass Core Web Vitals (LCP 2.5 s, INP 138 ms, CLS 0 at the 75th percentile). In the mobile lab test the score is 35 (desktop 33) and the largest element appears at 13.6 s; 1.26 MB of the 1.9 MB page is a 3D molecule viewer library loaded from a public CDN on every page, with 7.6 s of render-blocking requests, 945 KB of unused JavaScript and five accessibility issues.Source
  • 21

    The site offers [email protected] but no press kit, while Chai is covered by the New York Times, Forbes, Endpoints and Bloomberg. Reporters need facts fast: founders, funding, partners, models, logos.

    Medium impactLow effort First result in 2 weeks Brand and Marketing lead

    First action

    Write the fact sheet.

    How to measure it

    Press page visits

    Now
    –
    Target
    500 a month
    By
    2 quarters

    Steps

    1. 1

      Write fact sheet

      Funding, partners, models.

      Brand and Marketing lead 2 days

    2. 2

      Collect assets

      Logos and photos.

      Brand and Marketing lead 2 days

    3. 3

      Bios

      Founders.

      Brand and Marketing lead 1 day

    4. 4

      Publish

      Press page.

      Design Engineer 1 day

    5. 5

      Link

      Footer and news.

      Design Engineer 1 hour

    6. 6

      Update

      Each announcement.

      Brand and Marketing lead ongoing

    First result
    2 weeks
    Cost
    $0
    Owner
    Brand and Marketing lead

    Smallest test

    Publish the fact sheet this week.

    Why it works

    Publish a press page: fact sheet (founded 2024, funding, investors, partners, models and dates), founder bios and photos, logos, recent coverage and a contact.

    Accurate facts in every story, and AI systems that summarize Chai correctly.

    Risks and how to handle them

    • Out-of-date facts

      Date the fact sheet.

    Evidence

    • Your websiteHomepage and Careers: the two main homepage statements ("Chai powers drug discovery programs at the world's leading pharmaceutical companies." and the "Our models learn..." paragraph) are split into one element per letter with no accessible label, so text tools read "C h a i p o w e r s ...". The Careers headline reads "Join and work one the most meaningful problems AI." Contact is by email only (info@ and [email protected]).Source
    • Your websiteResearch & News: the GSK collaboration (October 9, 2026) "Following Successful Wet-Lab Evaluation", reported by Endpoints as "its sixth pharma partner in nine months"; Bristol Myers Squibb (August 20), argenx (July 15), the $400M Series C (July 14), Novartis (July 13), Lilly TuneLab (June 18; TuneLab "crosses 100-member mark"), Pfizer (June 4), Eli Lilly (January 9), Series B $130M (December 2025). The homepage partner strip shows Novartis, Pfizer, Eli Lilly and argenx only.Source
    • Your websiteGSK post: "Chai's models generated designs to GSK targets, zero-shot without target-specific training. GSK conducted internal wet-lab testing of the designs, finding binders to all tested targets." The Series C post: "$400 million at a $3.8 billion valuation"; "Our latest model, Chai-3, is unlocking targets that have long resisted traditional computational and laboratory methods"; partners "have started adopting our models across their organizations". The Pfizer agreement includes "Chai-3, its most advanced model".Source

03

How Programmable can help

Where an idea in this playbook is something Programmable builds or runs, it's listed here with what we'd do. Everything else is yours to run.

Have it built

ProgrammableAgency

1 of the 21 ideas are things Programmable builds and runs for its customers: pages, outreach, prospect lists, booking flows and monitors. Pick one, or send the whole list.

Prospect lists1The list compiled from public sources, verified, deduplicated and delivered to your CRM.

A 30-minute session with the engineer who would build it, not a sales call. You leave with a plan whether or not you hire us.

Book a working session

Usually live within days.

Tools for the rest

ProgrammableTalk

Fill the events in this plan

These ideas are events. Talk gets registrants for them and tells you who's coming and what their company does before the day.

Plan an event (opens programmable.talk in a new tab)
ProgrammableDigital

Show it, don't just describe it

These ideas need something to show: a demo, a video, an animation, graphics or a deck. Digital turns screenshots or the site into all of them, in the company's own brand.

Make a demo (opens programmable.digital in a new tab)
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See every playbook and website review

Independent research. Programmable wrote this playbook from public sources, as they stood on October 23, 2026, and cites them throughout. Chai Discovery did not commission, review or endorse it, and Programmable is not affiliated with Chai Discovery. Company and product names are trademarks of their owners, used only to identify them. The ideas are suggestions and opinion, not professional, legal or financial advice, and not statements about how Chai Discovery runs its business.

Something wrong, or do you represent Chai Discovery? Email [email protected] and we will correct it or take it down.

30/60/90 roadmap

What to focus on in each month, and the ideas that carry it.

  1. Days 1 to 308 ideas

    Unique page metadata and a full sitemap, Chai-3 on the Platform page, all six partners on the homepage, the Careers fix, routed access forms and readable homepage text; the press kit and viewer loading.

  2. Days 31 to 609 ideas

    The evaluation offer, a results page, JPM plan, partner stories, researcher posts, the TuneLab page, the Chai-1 community, academic program and internal champions.

  3. Days 61 to 904 ideas

    Commit to segment pricing, API access, an open design challenge and the engineer residency.

The research behind the plan

3 research areas, each summarised in a few lines. Open any of them for the full detail.

Customers

What customers say

Customers value zero-shot designs that bind in the lab. The most cited problem: slow, costly antibody discovery by screening.

  • High success rates without large screens
  • Hard targets such as membrane proteins
  • In their words: “zero-shot”

Market

Competitive landscape

5 competitors compared: Isomorphic Labs, Generate:Biomedicines, Nabla Bio, Latent Labs and 1 more.

  • Gap to exploit: Standard, verifiable model evaluations for pharma
  • Isomorphic Labs: Focus on its own and partnered programs
  • Generate:Biomedicines: Competes with potential partners

Hiring signals

Chai is moving from research lab to commercial platform.

  • Brand and Marketing: First marketing hire: online presence, JPM, researcher reach. Ideas 1, 2, 3, 4, 9, 11, 21.
  • Business Development: Deal volume accelerating. Ideas 5, 7, 12.
  • Engagement Management: Partnership health and growth. Ideas 10, 15.

From the team that wrote this playbook

All products
  • ProgrammableAgencyWorking AI systems in days, not quarters (opens programmable.agency in a new tab)
  • ProgrammableInfoAn agent that finds, researches and asks first (opens programmable.info in a new tab)
  • ProgrammableDigitalScreenshots in, an animated product demo out (opens programmable.digital in a new tab)
  • ProgrammableWatchKnow the day a supplier falls out of compliance (opens programmable.watch in a new tab)
  • ProgrammableTalkGet registrants for your events, and know who’s coming (opens programmable.talk in a new tab)
  • ProgrammablePageText what you need, your customer gets a page that works (opens programmable.page in a new tab)
  • ProgrammableCommunityForums with labelled AI members, never empty (opens programmable.community in a new tab)
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