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Generated Oct 23, 2026
  1. Programmable
  2. Playbooks
  3. Loyal
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growth playbook · Oct 23, 2026

loyal.com (opens in a new tab)

Loyal growth playbook

Diagnosis

Loyal is preparing to launch a category that does not exist yet, and is hiring a VP of Marketing to build vet and consumer marketing for LOY-002 while regulatory and manufacturing hires finish the last FDA section. Before approval, growth means trusted education and a measured, launch-ready audience.

The site's signup asks only for an email, so the list cannot show which dogs it covers; pages share one description and there is no sitemap. This playbook makes the list launch-ready, separates the vet path, fixes the search basics, then builds tested category language, measured vet engagement, STAY practice advocates and education tools, with regulatory review on every step and no efficacy claims.

Growth Score

6/10

Biggest Opportunity

Arrive at approval with a known, segmented audience of owners and prepared vets, built through education rather than promotion.

Biggest Risk

Approval timing is not guaranteed and pre-approval promotion is restricted, so any copy that sounds like a product claim could harm trust and regulatory standing.

01

Start here

The three moves to make first. Each one is written up in full below.

  1. 1

    Make "Be the first to know" a launch-ready list: ask the dog's age and weight and the owner's vet

    Add age, weight and ZIP fields to the form after regulatory review of the wording.

    High impact First result in 1 month
  2. 2

    Give vets their own signup path into the Learning Hub, not the owner newsletter

    Split the welcome email by contact type.

    High impact First result in 1 month
  3. 3

    Add a sitemap and a unique description to every page

    Generate the sitemap from the Next.js routes.

    Medium impact First result in 2 weeks

02

Your idea portfolio

21 ideas, grouped by when to run them. Open any idea for how to run it: the steps, who to approach, copy you can use, and how to measure it.

  • 6 ideas are marked Unexpected: plays you are unlikely to have tried.

Every idea placed by the effort it takes against the impact it could have. Quick wins sit top left; select a number to open that idea. The filters below narrow the list by status, timing, category and what Programmable can build.

Effort vs impactEach number is an idea. Select one to open it.
Impact →
Quick wins · 2Big bets · 6Fill-ins · 10Reconsider · 3
Effort →

Showing 21 of 21 ideas

This week 6

Quick wins with a clear first action.

  • 01

    Every Loyal page invites visitors to "Be the first to know when Loyal drugs are available", but the form takes only an email and an owner-or-vet checkbox. Loyal's three programs are defined by age and weight (LOY-002 for dogs 10+ and 14 lb+, LOY-001 for 7+ and 40 lb+, LOY-003 for 5+ and 60 lb+), so today the list cannot say how many sign-ups have a dog each program is meant for, where they live, or which vets they use. The new VP of Marketing is asked to hone key audiences and define how success is measured before approval; this list is the only first-party measure of demand Loyal has.

    High impactLow effort First result in 1 month Vice President

    First action

    Add age, weight and ZIP fields to the form after regulatory review of the wording.

    How to measure it

    Sign-ups with dog age and weight

    Now
    –
    Target
    60% of new sign-ups
    By
    60 days

    Steps

    1. 1

      Agree the fields

      Birth year, weight band, ZIP, optional clinic, with consent text.

      Vice President, Marketing 2 days

    2. 2

      Review wording

      Form, welcome email and privacy notice.

      Regulatory and legal review 3 days

    3. 3

      Update the form

      Same HubSpot form on every page; keep email the only required field.

      Marketing team 1 day

    4. 4

      Tag by program fit

      LOY-002, LOY-001/003 or not yet eligible.

      Marketing team 1 day

    5. 5

      Backfill

      One email asking existing subscribers to add their dog.

      Marketing team 1 week

    6. 6

      Report monthly

      Sign-ups by program fit, state and clinic.

      Vice President, Marketing monthly

    First result
    1 month
    Cost
    Staff time only
    Owner
    Vice President, Marketing

    Smallest test

    Add the fields to the form on /for-dog-owners only for two weeks and compare completion.

    Why it works

    Add three optional fields to the HubSpot form: the dog's birth year (or age), weight band, and ZIP code, plus an optional "your vet clinic" field. Tag each contact by program fit and send a short welcome email that explains, in approved language, where each program is in the FDA process. Ask existing subscribers to complete the same fields in one email. Report sign-ups by program fit and region every month.

    At approval, Loyal can tell the right owners on day one and show vets how many of their own clients are waiting. Until then, the list gives the VP of Marketing a real pre-approval metric (qualified sign-ups by program and region) instead of a raw email count, and the clinic field shows which practices to reach first.

    Ready to use

    ChecklistLaunch-ready signup form

    [ ] Email (required)
    [ ] Dog owner / veterinary professional
    [ ] Dog birth year (optional)
    [ ] Weight band: under 14 lb / 14-39 / 40-59 / 60+ (optional)
    [ ] ZIP code (optional)
    [ ] Your vet clinic (optional, with consent)
    [ ] Wording approved by regulatory and legal
    [ ] Tags: LOY-002 fit / big-dog fit / not yet eligible

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    • Longer forms lower sign-ups

      Keep the new fields optional and test the form against the current one.

    Evidence

    • Your websiteThe "Stay connected" / "Be the first to know" signup on every page is one HubSpot form with two fields: an email address and a checkbox "I'm a dog owner" or "I'm a veterinary professional". It asks nothing about the dog (age, weight, size) or the owner's vet or location.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
    • Your websiteFor dog owners page: LOY-002 is "intended for dogs aged 10 and older and weighing at least 14 lb"; LOY-001 is for dogs 7 and older weighing at least 40 lb (a vet-given long-acting injection) and LOY-003 for dogs 5 and older weighing at least 60 lb (a daily pill); all are developed under the FDA CVM expanded conditional approval (XCA) pathway; each claim is marked "FDA approval not guaranteed".Source
    • Your websiteHomepage (checked October 22, 2026): "We're developing the first longevity drugs for dogs"; "3 drug programs in development", "70 veterinary practices in STAY clinical trial", "1,317 dogs enrolled"; LOY-002 is for "Dogs age 10+, 14+ lb", with "2/3 major requirements completed. FDA approval not guaranteed"; calls to action "Be the first to know when Loyal drugs are available" and "Earn free CE credit in canine aging"; press logos from Forbes, NBC News, The New York Times, The Washington Post and The Wall Street Journal.Source
  • 02

    Vets who tick "I'm a veterinary professional" join the same two-field list as owners. The free RACE-approved Learning Hub is Loyal's strongest vet asset, and vet trust before approval is half of the VP of Marketing's brief.

    High impactLow effort First result in 1 month Vice President

    First action

    Split the welcome email by contact type.

    How to measure it

    Vet sign-ups starting CE within 30 days

    Now
    –
    Target
    40%
    By
    90 days

    Steps

    1. 1

      Split the list

      Owner and vet journeys.

      Marketing team 1 day

    2. 2

      Write the series

      Hub, brief, frailty index, publications.

      VP of Clinical and Veterinary Medicine 1 week

    3. 3

      Review

      Vet-facing wording.

      Regulatory and legal review 3 days

    4. 4

      Add practice fields

      Practice, role, senior share.

      Marketing team 1 day

    5. 5

      Track CE by practice

      Starts and completions.

      Marketing team 1 week

    6. 6

      Report

      Engaged practices by state.

      Vice President, Marketing monthly

    First result
    1 month
    Cost
    Staff time only
    Owner
    Vice President, Marketing

    Smallest test

    Send the vet welcome email to the vets already on the list.

    Why it works

    Send vets to a vet welcome series: the Learning Hub, the product brief, the Canine Frailty Index and publications. Ask for practice name, role (DVM, technician, manager) and senior patient share. Track course starts and completions per practice.

    Vets prescribe; knowing which practices have engaged is the base of a launch plan.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteThe "Stay connected" / "Be the first to know" signup on every page is one HubSpot form with two fields: an email address and a checkbox "I'm a dog owner" or "I'm a veterinary professional". It asks nothing about the dog (age, weight, size) or the owner's vet or location.Source
    • Your websiteContinuing education: the Loyal Learning Hub offers free RACE-approved courses for "DVMs, technicians, and the entire veterinary team", from a 16-minute crash course to 1-hour courses ("Dog longevity 101/201/301", "Top Five Health Conditions in Senior Dogs").Source
    • Your websiteFor vets page: downloadable product brief, Canine Frailty Index and canine aging resources; a list of peer-reviewed publications; a Healthspan Study of 451 dogs validating the vet-assessed Canine Frailty Index and an owner-assessed quality-of-life measure; vet questions go to a shared vets@ inbox.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
  • 03

    Loyal's main pages (for dog owners, for vets, clinical trials, products, CE and more) all share one meta description, none has a canonical tag, /sitemap.xml returns 404 and robots.txt names no sitemap. The homepage structured data still says 2021.

    Medium impactLow effort First result in 2 weeks VP

    First action

    Generate the sitemap from the Next.js routes.

    How to measure it

    Pages with unique descriptions

    Now
    –
    Target
    100%
    By
    30 days

    Steps

    1. 1

      Build sitemap

      Pages and posts.

      VP, Product and Engineering 1 day

    2. 2

      Register

      robots.txt and Search Console.

      VP, Product and Engineering 1 hour

    3. 3

      Write descriptions

      One per page.

      Marketing team 1 day

    4. 4

      Review

      Descriptions for claims.

      Regulatory and legal review 1 day

    5. 5

      Canonicals

      Self-referencing.

      VP, Product and Engineering 2 hours

    6. 6

      Structured data

      Organization and article dates.

      VP, Product and Engineering 1 day

    First result
    2 weeks
    Cost
    $0
    Owner
    VP, Product and Engineering

    Smallest test

    Ship the sitemap today.

    Why it works

    Generate a sitemap with all pages and 58 posts, add it to robots.txt and Search Console, write a description per page (owners, vets, STAY, CE), add self-canonicals and update the structured data.

    Search results and link previews then match what each audience is looking for, and new posts get found faster.

    Risks and how to handle them

    • Descriptions drift into claims

      Review them like any copy.

    Evidence

    • Your websitePage metadata (checked October 22, 2026): /, /for-dog-owners, /for-vets, /clinical-trials, /products, /blog, /continuing-education, /about, /careers and /contact all use the same meta description ("Loyal is a clinical-stage veterinary medicine company working on giving dogs longer, healthier lives."); none has a canonical tag; /sitemap.xml returns 404 and robots.txt names no sitemap; the homepage structured data says it was last modified in 2021.Source
    • Your websiteBlog: 58 posts in six categories (Aging thesis, Senior dog science, Big dog science, Developing drugs, Dog health, Loyal news), including "Why do big dogs have unusually short lifespans compared to small dogs", "How old is your dog really? Predicting age through methylation", "Signs of senior years" and "What is FDA conditional approval".Source
  • 04

    The banner on every page sends visitors to the LOY-003 announcement, and that post points readers to loyal.com/our-approach for more, which returns 404. The readers most curious about the science hit a dead end.

    Medium impactLow effort First result in 1 week Marketing team

    First action

    Change the link in the post.

    How to measure it

    Broken internal links in posts

    Now
    –
    Target
    0
    By
    2 weeks

    Steps

    1. 1

      Fix the link

      In the LOY-003 post.

      Marketing team 1 hour

    2. 2

      Add a redirect

      /our-approach to the right page.

      VP, Product and Engineering 1 hour

    3. 3

      Crawl posts

      All 58.

      Marketing team 1 day

    4. 4

      Fix others

      Any found.

      Marketing team 1 day

    5. 5

      Add a check

      Monthly crawl.

      VP, Product and Engineering 1 day

    6. 6

      Track

      Clicks from milestone posts.

      Marketing team monthly

    First result
    1 week
    Cost
    $0
    Owner
    Marketing team

    Smallest test

    Add the redirect today.

    Why it works

    Point the link to the right page (products or for dog owners) or publish an "our approach" page, then check every post for broken internal links each month.

    Milestone posts get the most traffic and press links, so their onward path matters most.

    Risks and how to handle them

    • Old links in press

      Keep redirects permanent.

    Evidence

    • Your websiteThe September 16, 2026 post "Longer lives for bigger dogs? Loyal earns third RXE acceptance from the FDA", which the banner on every page links to ("Big news for big dogs!"), sends readers to loyal.com/our-approach for "more on our approach to aging"; that address returned 404 on two checks on October 22, 2026.Source
    • Your websiteBlog: 58 posts in six categories (Aging thesis, Senior dog science, Big dog science, Developing drugs, Dog health, Loyal news), including "Why do big dogs have unusually short lifespans compared to small dogs", "How old is your dog really? Predicting age through methylation", "Signs of senior years" and "What is FDA conditional approval".Source
  • 05

    Real visitors pass Core Web Vitals, but the homepage downloads 16 MB (mostly the hero video), the lab test on mobile shows 12.4 s to the main content, and real-user loading has slowed 54%. Press spikes bring mobile visitors on slower connections.

    Medium impactLow effort First result in 2 weeks VP

    First action

    Swap the hero video for a poster image on mobile.

    How to measure it

    Homepage download on mobile

    Now
    –
    Target
    Under 3 MB
    By
    30 days

    Steps

    1. 1

      Poster first

      Image before video.

      VP, Product and Engineering 1 day

    2. 2

      Smaller video

      Adaptive and lazy.

      VP, Product and Engineering 2 days

    3. 3

      Unblock render

      Defer non-critical scripts.

      VP, Product and Engineering 2 days

    4. 4

      Budget

      Fail builds above it.

      VP, Product and Engineering 1 day

    5. 5

      Lab check

      PageSpeed mobile.

      VP, Product and Engineering 1 day

    6. 6

      Field check

      Chrome UX Report.

      VP, Product and Engineering 1 month

    First result
    2 weeks
    Cost
    Engineering time only
    Owner
    VP, Product and Engineering

    Smallest test

    Test the poster image on mobile for one week.

    Why it works

    Serve a poster image first and stream a smaller video only on fast connections, remove render-blocking requests, and set a page-weight budget.

    A faster homepage keeps real users passing as traffic grows and helps sign-ups on mobile after news.

    Risks and how to handle them

    • Brand loses impact

      Keep the video on desktop.

    Evidence

    • Google PageSpeedPageSpeed for the homepage on mobile (October 22, 2026): performance 57 (desktop 83), Largest Contentful Paint 12.4 s in the lab, a 16 MB download (mostly the hero video), about 3.5 s of render-blocking requests. Real visitors pass Core Web Vitals (LCP 2.0 s, INP 143 ms), though the Chrome UX Report shows LCP 54% slower than before.Source
    • Your websiteHomepage (checked October 22, 2026): "We're developing the first longevity drugs for dogs"; "3 drug programs in development", "70 veterinary practices in STAY clinical trial", "1,317 dogs enrolled"; LOY-002 is for "Dogs age 10+, 14+ lb", with "2/3 major requirements completed. FDA approval not guaranteed"; calls to action "Be the first to know when Loyal drugs are available" and "Earn free CE credit in canine aging"; press logos from Forbes, NBC News, The New York Times, The Washington Post and The Wall Street Journal.Source
  • 06

    Two of Loyal's three programs are for big dogs, and the LOY-003 post explains that Great Danes average 6-8 years while Chihuahuas can live to 20. There is no page for big-dog owners; that content sits in blog posts.

    High impactMedium effort First result in 1 month Vice President

    First action

    Outline the hub from existing big-dog posts.

    How to measure it

    Sign-ups with a 40 lb+ dog

    Now
    –
    Target
    +50%
    By
    90 days

    Steps

    1. 1

      Gather posts

      Big dog science category.

      Marketing team 1 day

    2. 2

      Write hub

      Education first.

      Marketing team 1 week

    3. 3

      Vet review

      Accuracy.

      VP of Clinical and Veterinary Medicine 3 days

    4. 4

      Regulatory review

      No efficacy claims.

      Regulatory and legal review 1 week

    5. 5

      Publish

      With signup.

      VP, Product and Engineering 1 day

    6. 6

      Measure

      Big-dog sign-ups.

      Vice President, Marketing monthly

    First result
    1 month
    Cost
    Staff time only
    Owner
    Vice President, Marketing

    Smallest test

    Publish one page on giant-breed lifespans.

    Why it works

    Build an owner education hub on why big dogs age faster: breed lifespan facts, senior signs that start earlier, care tips, the published science, and the signup. Keep it disease education; refer to programs only in approved milestone language.

    Big-dog owners search for this, and they are a clear audience the VP of Marketing can grow before approval.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your blogLOY-003 post: "big dogs like Great Danes have an average life expectancy of 6-8 years, whereas small dogs like Chihuahuas can live up to 20 years", and big dogs can have "~2-30X as much IGF-1" as medium and small dogs.Source
    • Your websiteFor dog owners page: LOY-002 is "intended for dogs aged 10 and older and weighing at least 14 lb"; LOY-001 is for dogs 7 and older weighing at least 40 lb (a vet-given long-acting injection) and LOY-003 for dogs 5 and older weighing at least 60 lb (a daily pill); all are developed under the FDA CVM expanded conditional approval (XCA) pathway; each claim is marked "FDA approval not guaranteed".Source
    • Your websiteBlog: 58 posts in six categories (Aging thesis, Senior dog science, Big dog science, Developing drugs, Dog health, Loyal news), including "Why do big dogs have unusually short lifespans compared to small dogs", "How old is your dog really? Predicting age through methylation", "Signs of senior years" and "What is FDA conditional approval".Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source

This quarter 10

The core plays for the next three months.

  • 07

    The VP of Marketing's near-term job includes "early messaging and positioning work for aging care" for two audiences, and the role notes how hard it is to be rigorous for vets yet warm for owners.

    High impactMedium effort First result in 1 quarter Vice President

    First action

    Write five framings.

    How to measure it

    Framings tested with 1,000+ responses

    Now
    –
    Target
    5
    By
    1 quarter

    Steps

    1. 1

      Write framings

      Five.

      Vice President, Marketing 1 week

    2. 2

      Regulatory review

      Each framing.

      Regulatory and legal review 1 week

    3. 3

      Owner survey

      Segments of the list.

      Marketing team 2 weeks

    4. 4

      Vet panel

      CE learners.

      VP of Clinical and Veterinary Medicine 2 weeks

    5. 5

      Analyze

      By audience.

      Senior Statistician, Research & Development 1 week

    6. 6

      Decide

      Core language.

      Vice President, Marketing 1 week

    First result
    1 quarter
    Cost
    Survey tools
    Owner
    Vice President, Marketing

    Smallest test

    Test two framings in subject lines.

    Why it works

    Run message tests with segments of the list and with vets: framings of aging as a condition, healthspan, quality of life. Use surveys and email subject tests; keep all copy to disease education and approved milestones.

    Category language chosen with data now becomes launch copy that is already tested.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
    • Your websiteThe "Stay connected" / "Be the first to know" signup on every page is one HubSpot form with two fields: an email address and a checkbox "I'm a dog owner" or "I'm a veterinary professional". It asks nothing about the dog (age, weight, size) or the owner's vet or location.Source
    • Your websiteBlog: 58 posts in six categories (Aging thesis, Senior dog science, Big dog science, Developing drugs, Dog health, Loyal news), including "Why do big dogs have unusually short lifespans compared to small dogs", "How old is your dog really? Predicting age through methylation", "Signs of senior years" and "What is FDA conditional approval".Source
  • 08

    The free RACE-approved Learning Hub reaches DVMs and technicians; the commercial plan will need a list of practices that already understand the science.

    High impactMedium effort First result in 1 quarter VP of Commercial

    First action

    Export CE completions by practice.

    How to measure it

    Practices with a completed course

    Now
    –
    Target
    2,000
    By
    2 quarters

    Steps

    1. 1

      Export data

      Completions by practice.

      Marketing team 1 week

    2. 2

      Live sessions

      Quarterly with clinical team.

      VP of Clinical and Veterinary Medicine quarterly

    3. 3

      Map

      Practices by state.

      Marketing team 2 weeks

    4. 4

      New courses

      Senior care topics.

      VP of Clinical and Veterinary Medicine 1 quarter

    5. 5

      Review

      All course material.

      Regulatory and legal review ongoing

    6. 6

      Plan coverage

      From the map.

      VP of Commercial 1 month

    First result
    1 quarter
    Cost
    Course production
    Owner
    VP of Commercial

    Smallest test

    Invite last quarter's completers to one live session.

    Why it works

    Track CE completions by practice, invite completers to live sessions with the clinical team, and build a "practices engaged" map. Use it to plan field coverage at launch.

    Engaged practices are the first prescribers, and the map shows where to start.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteContinuing education: the Loyal Learning Hub offers free RACE-approved courses for "DVMs, technicians, and the entire veterinary team", from a 16-minute crash course to 1-hour courses ("Dog longevity 101/201/301", "Top Five Health Conditions in Senior Dogs").Source
    • Your websiteFor vets page: downloadable product brief, Canine Frailty Index and canine aging resources; a list of peer-reviewed publications; a Healthspan Study of 451 dogs validating the vet-assessed Canine Frailty Index and an owner-assessed quality-of-life measure; vet questions go to a shared vets@ inbox.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
  • 09

    Seventy practices across the US run the STAY study with over 1,300 dogs. They know Loyal's rigor first-hand and see senior dogs every day.

    High impactMedium effort First result in 2 quarters VP of Clinical and Veterinary…

    First action

    Ask five STAY practices what they would want.

    How to measure it

    Reference practices

    Now
    –
    Target
    30
    By
    2 quarters

    Steps

    1. 1

      Design the program

      Roles and limits.

      VP of Clinical and Veterinary Medicine 2 weeks

    2. 2

      Protect the study

      No effect on blinding.

      Senior Statistician, Research & Development 1 week

    3. 3

      Review

      Program and materials.

      Regulatory and legal review 2 weeks

    4. 4

      Invite

      All 70 practices.

      VP of Clinical and Veterinary Medicine 1 month

    5. 5

      Run councils

      Twice a year.

      VP of Clinical and Veterinary Medicine 6 months

    6. 6

      Plan launch role

      Peer talks.

      VP of Commercial 1 quarter

    First result
    2 quarters
    Cost
    Staff time and honoraria
    Owner
    VP of Clinical and Veterinary Medicine

    Smallest test

    Hold one call with five STAY practices.

    Why it works

    Invite STAY practices to an advisory and reference program for after approval: feedback on materials, peer talks at conferences, and stories of running a trial (process, not results). Keep study integrity and blinding untouched.

    Vets trust other vets, and these clinics are already partners.

    Risks and how to handle them

    • Study integrity

      Keep the program separate from study conduct.

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteClinical trials page: STAY is a double-blinded, placebo-controlled study of 1,300+ dogs at 70 practices, now "Fully Enrolled", lasting up to four years; the page invites visitors "Interested in future studies? Join our newsletter" to the same signup form.Source
    • Your websiteHomepage (checked October 22, 2026): "We're developing the first longevity drugs for dogs"; "3 drug programs in development", "70 veterinary practices in STAY clinical trial", "1,317 dogs enrolled"; LOY-002 is for "Dogs age 10+, 14+ lb", with "2/3 major requirements completed. FDA approval not guaranteed"; calls to action "Be the first to know when Loyal drugs are available" and "Earn free CE credit in canine aging"; press logos from Forbes, NBC News, The New York Times, The Washington Post and The Wall Street Journal.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
  • 10

    Loyal has a "Signs of senior years" guide, an owner-assessed quality-of-life measure validated in the Healthspan Study, and blog posts on dog age. Owners search for when their dog is "senior".

    Medium impactMedium effort First result in 1 quarter Marketing team

    First action

    Turn the PDF guide into ten questions.

    How to measure it

    Check completions

    Now
    –
    Target
    20,000
    By
    2 quarters

    Steps

    1. 1

      Write questions

      From the guide.

      Marketing team 1 week

    2. 2

      Vet review

      Accuracy.

      VP of Clinical and Veterinary Medicine 1 week

    3. 3

      Regulatory review

      No diagnosis or claims.

      Regulatory and legal review 1 week

    4. 4

      Build

      Simple web page.

      VP, Product and Engineering 2 weeks

    5. 5

      Promote

      Social and posts.

      Marketing team ongoing

    6. 6

      Measure

      Completions and sign-ups.

      Marketing team monthly

    First result
    1 quarter
    Cost
    Engineering time
    Owner
    Marketing team

    Smallest test

    Publish a static version first.

    Why it works

    Build a short interactive check: dog age, weight and signs noticed, with education and "talk to your vet" prompts, and the signup at the end. No diagnosis, no product claims.

    Useful tools earn links and sign-ups and bring owners to their vets.

    Risks and how to handle them

    • Seen as medical advice

      Clear "talk to your vet" framing.

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteFor vets page: downloadable product brief, Canine Frailty Index and canine aging resources; a list of peer-reviewed publications; a Healthspan Study of 451 dogs validating the vet-assessed Canine Frailty Index and an owner-assessed quality-of-life measure; vet questions go to a shared vets@ inbox.Source
    • Your websiteBlog: 58 posts in six categories (Aging thesis, Senior dog science, Big dog science, Developing drugs, Dog health, Loyal news), including "Why do big dogs have unusually short lifespans compared to small dogs", "How old is your dog really? Predicting age through methylation", "Signs of senior years" and "What is FDA conditional approval".Source
    • Your websiteThe "Stay connected" / "Be the first to know" signup on every page is one HubSpot form with two fields: an email address and a checkbox "I'm a dog owner" or "I'm a veterinary professional". It asks nothing about the dog (age, weight, size) or the owner's vet or location.Source
  • 11

    Loyal has 58 posts, publications and regular FDA milestones, but the signup promises only "more details on our products". Subscribers hear from Loyal at milestones.

    Medium impactLow effort First result in 1 quarter Marketing team

    First action

    Plan three months of issues.

    How to measure it

    Open rate

    Now
    –
    Target
    45%
    By
    2 quarters

    Steps

    1. 1

      Plan issues

      Three months.

      Marketing team 1 week

    2. 2

      Write

      Owner and vet editions.

      Marketing team monthly

    3. 3

      Review

      Each issue.

      Regulatory and legal review monthly

    4. 4

      Send

      Segmented.

      Marketing team monthly

    5. 5

      Measure

      Opens and clicks.

      Marketing team monthly

    6. 6

      Prune

      Inactive contacts.

      Marketing team quarterly

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    Marketing team

    Smallest test

    Send the first owner issue.

    Why it works

    Send one monthly email per audience: owners get senior care and science stories; vets get publications and CE. Milestones go out as approved news.

    A list that hears from Loyal monthly is warm at launch.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteThe "Stay connected" / "Be the first to know" signup on every page is one HubSpot form with two fields: an email address and a checkbox "I'm a dog owner" or "I'm a veterinary professional". It asks nothing about the dog (age, weight, size) or the owner's vet or location.Source
    • Your websiteBlog: 58 posts in six categories (Aging thesis, Senior dog science, Big dog science, Developing drugs, Dog health, Loyal news), including "Why do big dogs have unusually short lifespans compared to small dogs", "How old is your dog really? Predicting age through methylation", "Signs of senior years" and "What is FDA conditional approval".Source
    • Your blogSeries C announcement (February 11, 2026): $100 million to advance LOY-002 toward FDA approval; two of three major requirements for expanded conditional approval completed; STAY fully enrolled; a limited-time merch store with "100% of proceeds going to Muttville", a San Francisco senior dog rescue.Source
  • 12

    Loyal is covered by Forbes, NBC, The New York Times, The Washington Post and The Wall Street Journal, and the VP of Marketing will own company communications. Press contact is an email address.

    Medium impactLow effort First result in 1 quarter Vice President

    First action

    Draft the fact sheet.

    How to measure it

    Articles per milestone

    Now
    –
    Target
    +30%
    By
    2 quarters

    Steps

    1. 1

      Fact sheet

      Current facts.

      Vice President, Marketing 1 week

    2. 2

      Timeline

      All milestones.

      Marketing team 1 week

    3. 3

      Assets

      Images and bios.

      Marketing team 1 week

    4. 4

      Review

      All copy.

      Regulatory and legal review 1 week

    5. 5

      Publish

      Newsroom page.

      VP, Product and Engineering 1 day

    6. 6

      Update

      Each milestone.

      Marketing team ongoing

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    Vice President, Marketing

    Smallest test

    Publish the timeline first.

    Why it works

    Publish a newsroom: milestone timeline (RXE, TAS, STAY enrollment, funding), fact sheet, approved images and spokesperson bios, and the press list signup.

    Journalists cover milestones faster with facts in one place, and consistent facts reduce errors.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteHomepage (checked October 22, 2026): "We're developing the first longevity drugs for dogs"; "3 drug programs in development", "70 veterinary practices in STAY clinical trial", "1,317 dogs enrolled"; LOY-002 is for "Dogs age 10+, 14+ lb", with "2/3 major requirements completed. FDA approval not guaranteed"; calls to action "Be the first to know when Loyal drugs are available" and "Earn free CE credit in canine aging"; press logos from Forbes, NBC News, The New York Times, The Washington Post and The Wall Street Journal.Source
    • Your blogSeries C announcement (February 11, 2026): $100 million to advance LOY-002 toward FDA approval; two of three major requirements for expanded conditional approval completed; STAY fully enrolled; a limited-time merch store with "100% of proceeds going to Muttville", a San Francisco senior dog rescue.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
  • 13

    For the Series C, Loyal gave 100% of merch proceeds to Muttville, a senior dog rescue. Senior rescues reach exactly the owners who care about aging dogs.

    Medium impactLow effort First result in 1 quarter Vice President

    First action

    Ask Muttville about a recurring program.

    How to measure it

    Rescue partners

    Now
    –
    Target
    10
    By
    2 quarters

    Steps

    1. 1

      Shortlist

      Senior rescues.

      Marketing team 2 weeks

    2. 2

      Design

      Program and giving.

      Vice President, Marketing 2 weeks

    3. 3

      Review

      Content.

      Regulatory and legal review 1 week

    4. 4

      Launch

      With one partner.

      Marketing team 1 month

    5. 5

      Expand

      Regional rescues.

      Marketing team 1 quarter

    6. 6

      Measure

      Reach and sign-ups.

      Marketing team monthly

    First result
    1 quarter
    Cost
    Donations
    Owner
    Vice President, Marketing

    Smallest test

    Run one adoption story series.

    Why it works

    Build a recurring senior-rescue program: adoption stories, shared education content and an annual giving moment tied to company milestones.

    Doing good for senior dogs builds the brand without paid media, a bonus the VP role names.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your blogSeries C announcement (February 11, 2026): $100 million to advance LOY-002 toward FDA approval; two of three major requirements for expanded conditional approval completed; STAY fully enrolled; a limited-time merch store with "100% of proceeds going to Muttville", a San Francisco senior dog rescue.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
  • 14

    Every dog photo on Loyal's site carries a name and age ("Abby, Age 13"). That format invites owners to share their own senior dogs.

    Medium impactLow effort First result in 1 quarter Marketing team

    First action

    Ask the list for ten senior dog photos.

    How to measure it

    Instagram-sourced sign-ups

    Now
    –
    Target
    1,000
    By
    2 quarters

    Steps

    1. 1

      Consent form

      Photo release.

      Marketing team 1 week

    2. 2

      Collect

      From the list.

      Marketing team ongoing

    3. 3

      Post weekly

      Name and age.

      Marketing team weekly

    4. 4

      Moderate

      No product claims.

      Regulatory and legal review ongoing

    5. 5

      Link

      Education and signup.

      Marketing team weekly

    6. 6

      Measure

      Sign-ups.

      Marketing team monthly

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    Marketing team

    Smallest test

    Post five owner dogs.

    Why it works

    Run a weekly owner feature with name and age, with consent, linking to education posts and the signup. Keep comments moderated for medical claims.

    User stories spread without paid budget and keep the focus on dogs, not products.

    Risks and how to handle them

    • Claims in comments

      Moderation rules.

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteHomepage (checked October 22, 2026): "We're developing the first longevity drugs for dogs"; "3 drug programs in development", "70 veterinary practices in STAY clinical trial", "1,317 dogs enrolled"; LOY-002 is for "Dogs age 10+, 14+ lb", with "2/3 major requirements completed. FDA approval not guaranteed"; calls to action "Be the first to know when Loyal drugs are available" and "Earn free CE credit in canine aging"; press logos from Forbes, NBC News, The New York Times, The Washington Post and The Wall Street Journal.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
  • 15

    The VP of Marketing must define "how we measure success in this pre-approval phase" and "operate without a scoreboard".

    Medium impactMedium effort First result in 1 quarter Vice President

    First action

    Draft five survey questions.

    How to measure it

    Baseline survey completed

    Now
    –
    Target
    1
    By
    1 quarter

    Steps

    1. 1

      Questions

      Five per audience.

      Vice President, Marketing 1 week

    2. 2

      Panel

      Vets and owners.

      Marketing team 2 weeks

    3. 3

      Run

      Baseline.

      Marketing team 1 month

    4. 4

      Analyze

      With statistics.

      Senior Statistician, Research & Development 2 weeks

    5. 5

      Combine

      List and CE data.

      Marketing team 1 week

    6. 6

      Repeat

      Twice a year.

      Vice President, Marketing 6 months

    First result
    1 quarter
    Cost
    Panel costs
    Owner
    Vice President, Marketing

    Smallest test

    Survey CE learners first.

    Why it works

    Set a twice-yearly survey of vets and senior-dog owners: awareness of Loyal, understanding of aging as a target, trust. Combine with list growth by program fit and CE completions.

    A scoreboard lets a team of two decide what works before launch.

    Risks and how to handle them

    • Small samples

      Use a professional panel.

    Evidence

    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
    • Your websiteThe "Stay connected" / "Be the first to know" signup on every page is one HubSpot form with two fields: an email address and a checkbox "I'm a dog owner" or "I'm a veterinary professional". It asks nothing about the dog (age, weight, size) or the owner's vet or location.Source
    • Your websiteContinuing education: the Loyal Learning Hub offers free RACE-approved courses for "DVMs, technicians, and the entire veterinary team", from a 16-minute crash course to 1-hour courses ("Dog longevity 101/201/301", "Top Five Health Conditions in Senior Dogs").Source
  • 16

    Vet questions go to a shared vets@ address. Vets ask about the science, CE, the STAY study and future availability.

    Medium impactLow effort First result in 1 quarter VP of Clinical and Veterinary…

    First action

    Tag last month's vet emails by topic.

    How to measure it

    Median response

    Now
    –
    Target
    Under 1 business day
    By
    1 quarter

    Steps

    1. 1

      Tag emails

      Last month.

      VP of Clinical and Veterinary Medicine 2 days

    2. 2

      Build form

      Topic, practice, role.

      VP, Product and Engineering 1 week

    3. 3

      Route

      By topic.

      Marketing team 1 week

    4. 4

      Answers library

      Approved replies.

      Regulatory and legal review 2 weeks

    5. 5

      Track

      Time and topics.

      VP of Clinical and Veterinary Medicine monthly

    6. 6

      Feed content

      New CE topics.

      VP of Clinical and Veterinary Medicine quarterly

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    VP of Clinical and Veterinary Medicine

    Smallest test

    Tag one month of emails.

    Why it works

    Add a short vet contact form with topic, practice and role; send CE questions to marketing, science questions to the clinical team, and log topics to see what vets ask most.

    Fast, expert answers build trust, and the topics show what to teach next.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteFor vets page: downloadable product brief, Canine Frailty Index and canine aging resources; a list of peer-reviewed publications; a Healthspan Study of 451 dogs validating the vet-assessed Canine Frailty Index and an owner-assessed quality-of-life measure; vet questions go to a shared vets@ inbox.Source
    • Your websiteContinuing education: the Loyal Learning Hub offers free RACE-approved courses for "DVMs, technicians, and the entire veterinary team", from a 16-minute crash course to 1-hour courses ("Dog longevity 101/201/301", "Top Five Health Conditions in Senior Dogs").Source

Big bets 3

Larger plays that can change the trajectory.

  • 17

    At approval, owners on the list will ask where to go; vets will need to know who is asking. The list (idea 1) and engaged practices (idea 8) are the inputs.

    High impactHigh effort First result in 3 quarters VP of Commercial

    First action

    Map list sign-ups by ZIP against engaged practices.

    How to measure it

    Opt-in practices in the finder

    Now
    –
    Target
    1,500
    By
    3 quarters

    Steps

    1. 1

      Map demand

      Sign-ups by ZIP.

      Marketing team 1 month

    2. 2

      Practice opt-in

      Finder listing.

      VP of Commercial 1 quarter

    3. 3

      Build

      Finder and emails.

      VP, Product and Engineering 1 quarter

    4. 4

      Review

      Whole system.

      Regulatory and legal review 1 month

    5. 5

      Test

      Dry run.

      Marketing team 1 month

    6. 6

      Switch on

      After approval only.

      VP of Commercial at approval

    First result
    3 quarters
    Cost
    Engineering time
    Owner
    VP of Commercial

    Smallest test

    Map one state.

    Why it works

    Prepare a system that, on approval, tells each owner which nearby practices have completed Loyal CE (opt-in practices only), and tells practices how many local owners are waiting. Build and test it now; switch it on only after approval and regulatory clearance.

    Launch day demand goes to prepared vets instead of confused calls.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    • Approval timing

      Keep it dormant until cleared.

    Evidence

    • Your websiteThe "Stay connected" / "Be the first to know" signup on every page is one HubSpot form with two fields: an email address and a checkbox "I'm a dog owner" or "I'm a veterinary professional". It asks nothing about the dog (age, weight, size) or the owner's vet or location.Source
    • Your websiteContinuing education: the Loyal Learning Hub offers free RACE-approved courses for "DVMs, technicians, and the entire veterinary team", from a 16-minute crash course to 1-hour courses ("Dog longevity 101/201/301", "Top Five Health Conditions in Senior Dogs").Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
  • 18

    Loyal has peer-reviewed publications, a 451-dog Healthspan Study and a canine aging atlas. Owners and vets lack one trusted yearly summary on senior dog health.

    High impactMedium effort First result in 3 quarters VP of Clinical and Veterinary…

    First action

    Pick five findings from publications.

    How to measure it

    Report downloads

    Now
    –
    Target
    10,000
    By
    1 year

    Steps

    1. 1

      Pick findings

      Published only.

      VP of Clinical and Veterinary Medicine 1 month

    2. 2

      Write

      Owner and vet editions.

      Marketing team 2 months

    3. 3

      Review

      Science and regulatory.

      Regulatory and legal review 1 month

    4. 4

      Design

      Charts.

      Marketing team 1 month

    5. 5

      Launch

      Press and CE.

      Vice President, Marketing 1 month

    6. 6

      Update

      Yearly.

      VP of Clinical and Veterinary Medicine yearly

    First result
    3 quarters
    Cost
    Design costs
    Owner
    VP of Clinical and Veterinary Medicine

    Smallest test

    Publish one chart from a paper.

    Why it works

    Publish a yearly report on how dogs age (frailty, quality of life, size and lifespan) from published data, with a vet edition for CE.

    Original, cited science earns press and links and makes Loyal the reference on dog aging.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your websiteFor vets page: downloadable product brief, Canine Frailty Index and canine aging resources; a list of peer-reviewed publications; a Healthspan Study of 451 dogs validating the vet-assessed Canine Frailty Index and an owner-assessed quality-of-life measure; vet questions go to a shared vets@ inbox.Source
    • Your websiteBlog: 58 posts in six categories (Aging thesis, Senior dog science, Big dog science, Developing drugs, Dog health, Loyal news), including "Why do big dogs have unusually short lifespans compared to small dogs", "How old is your dog really? Predicting age through methylation", "Signs of senior years" and "What is FDA conditional approval".Source
    • Your blogLOY-003 post: "big dogs like Great Danes have an average life expectancy of 6-8 years, whereas small dogs like Chihuahuas can live up to 20 years", and big dogs can have "~2-30X as much IGF-1" as medium and small dogs.Source
  • 19

    Senior dogs are a large cost for owners, and large animal-health companies already own vet relationships. Partnerships can widen reach at launch.

    Medium impactHigh effort First result in 4 quarters VP of Commercial

    First action

    List ten insurers and plan providers.

    How to measure it

    Partners in discussion

    Now
    –
    Target
    5
    By
    4 quarters

    Steps

    1. 1

      Map partners

      Insurers and plans.

      VP of Commercial 1 month

    2. 2

      Education first

      Co-branded senior content.

      Marketing team 1 quarter

    3. 3

      Review

      All content.

      Regulatory and legal review ongoing

    4. 4

      Early talks

      Coverage after approval.

      VP of Commercial 2 quarters

    5. 5

      Plan

      Launch terms.

      VP of Commercial 1 quarter

    6. 6

      Decide

      Partners.

      VP of Commercial 1 month

    First result
    4 quarters
    Cost
    Staff time only
    Owner
    VP of Commercial

    Smallest test

    Hold one insurer conversation.

    Why it works

    Map pet insurers and practice wellness plans that cover senior dogs, and open early conversations about senior-care education now and coverage after approval.

    Lower cost to owners and existing channels help adoption at launch.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Competitor researchOthers in senior dog health, from their own homepages: the Dog Aging Project ("Join the Dog Aging Project for a healthier future for dogs and humans"), a research program that enrolls owners and dogs; Leap Years, an "Aging Supplement For Dogs" sold as a soft chew; and large animal-health companies such as Zoetis ("Pet Care Made Simple") that already own vet relationships.Source
    • HiringVice President, Marketing (remote US, posted October 2, 2026): will "build out our consumer and vet marketing capabilities in preparation for the anticipated launch of our lead drug, LOY-002"; near term the work is "building the category with both audiences", "honing our key audiences and how best to reach them", "building concrete plans for launch" and "defining how we measure success in this pre-approval phase"; they "inherit our marketing team of two", report to the VP of Commercial, and also own company communications. Bonus: "You've marketed in a regulated category" and "built something people talked about without a large paid budget".Source
    • Your websiteFor dog owners page: LOY-002 is "intended for dogs aged 10 and older and weighing at least 14 lb"; LOY-001 is for dogs 7 and older weighing at least 40 lb (a vet-given long-acting injection) and LOY-003 for dogs 5 and older weighing at least 60 lb (a daily pill); all are developed under the FDA CVM expanded conditional approval (XCA) pathway; each claim is marked "FDA approval not guaranteed".Source

Wildcards 2

Unexpected experiments, each with a cheap way to test it.

  • 20

    Two programs are for big dogs, and Great Danes average only 6-8 years. Breed clubs gather the most committed owners of large and giant breeds.

    Medium impactLow effort First result in 1 quarter Marketing team

    First action

    List five giant-breed clubs.

    How to measure it

    Club talks

    Now
    –
    Target
    10
    By
    2 quarters

    Steps

    1. 1

      List clubs

      Large and giant breeds.

      Marketing team 1 week

    2. 2

      Talk deck

      Education only.

      VP of Clinical and Veterinary Medicine 2 weeks

    3. 3

      Review

      Deck.

      Regulatory and legal review 1 week

    4. 4

      Book talks

      Virtual first.

      Marketing team 1 month

    5. 5

      Follow up

      Newsletter.

      Marketing team ongoing

    6. 6

      Measure

      Sign-ups by club.

      Marketing team monthly

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    Marketing team

    Smallest test

    Give one talk.

    Why it works

    Offer breed clubs talks on why big dogs age faster, and invite members to the newsletter for future studies.

    Breed clubs are tight communities where one talk reaches committed owners.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    Evidence

    • Your blogLOY-003 post: "big dogs like Great Danes have an average life expectancy of 6-8 years, whereas small dogs like Chihuahuas can live up to 20 years", and big dogs can have "~2-30X as much IGF-1" as medium and small dogs.Source
    • Your websiteClinical trials page: STAY is a double-blinded, placebo-controlled study of 1,300+ dogs at 70 practices, now "Fully Enrolled", lasting up to four years; the page invites visitors "Interested in future studies? Join our newsletter" to the same signup form.Source
    • Your websiteFor dog owners page: LOY-002 is "intended for dogs aged 10 and older and weighing at least 14 lb"; LOY-001 is for dogs 7 and older weighing at least 40 lb (a vet-given long-acting injection) and LOY-003 for dogs 5 and older weighing at least 60 lb (a daily pill); all are developed under the FDA CVM expanded conditional approval (XCA) pathway; each claim is marked "FDA approval not guaranteed".Source
  • 21

    Loyal explains RXE, TAS and CMC and marks each step; the CMC hiring shows the last section is in progress. Owners follow along without a single place to see it.

    Medium impactLow effort First result in 1 quarter Vice President

    First action

    Draft the tracker from existing pages.

    How to measure it

    Tracker notifications sign-ups

    Now
    –
    Target
    5,000
    By
    2 quarters

    Steps

    1. 1

      Draft

      From pages.

      Marketing team 1 week

    2. 2

      Review

      Wording.

      Regulatory and legal review 1 week

    3. 3

      Build

      Simple page.

      VP, Product and Engineering 1 week

    4. 4

      Notify

      At milestones.

      Marketing team ongoing

    5. 5

      Explain

      Short posts.

      Marketing team ongoing

    6. 6

      Measure

      Follows.

      Marketing team monthly

    First result
    1 quarter
    Cost
    Staff time only
    Owner
    Vice President, Marketing

    Smallest test

    Publish the tracker for LOY-002.

    Why it works

    Make a simple public tracker of each program's approved milestones, with plain explanations and "get notified" at each step. No forecasts.

    People who follow a process become invested in it.

    Risks and how to handle them

    • Pre-approval promotion of an investigational drug

      Keep copy to company news, science and disease education; no safety or efficacy claims beyond the FDA milestones already published; regulatory and legal sign-off before anything goes live.

    • Seen as a promise

      Show completed steps only.

    Evidence

    • Your websiteFor dog owners page: LOY-002 is "intended for dogs aged 10 and older and weighing at least 14 lb"; LOY-001 is for dogs 7 and older weighing at least 40 lb (a vet-given long-acting injection) and LOY-003 for dogs 5 and older weighing at least 60 lb (a daily pill); all are developed under the FDA CVM expanded conditional approval (XCA) pathway; each claim is marked "FDA approval not guaranteed".Source
    • HiringThe other open roles are about the last approval step and supply: a Vice President, CMC Regulatory Affairs (posted October 2) to own the CMC regulatory program "from early development through approval and into post approval", a Principal Quality Assurance Specialist for external manufacturing, a Principal Scientist in CMC analytics and a Senior Statistician in R&D.Source
    • Your blogSeries C announcement (February 11, 2026): $100 million to advance LOY-002 toward FDA approval; two of three major requirements for expanded conditional approval completed; STAY fully enrolled; a limited-time merch store with "100% of proceeds going to Muttville", a San Francisco senior dog rescue.Source
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See every playbook and website review

Independent research. Programmable wrote this playbook from public sources, as they stood on October 23, 2026, and cites them throughout. Loyal did not commission, review or endorse it, and Programmable is not affiliated with Loyal. Company and product names are trademarks of their owners, used only to identify them. The ideas are suggestions and opinion, not professional, legal or financial advice, and not statements about how Loyal runs its business.

Something wrong, or do you represent Loyal? Email [email protected] and we will correct it or take it down.

30/60/90 roadmap

What to focus on in each month, and the ideas that carry it.

  1. Days 1 to 306 ideas

    Launch-ready signup fields, a vet signup path, sitemap and descriptions, the broken link, homepage weight and a big-dog hub.

  2. Days 31 to 6011 ideas

    Message tests, Learning Hub program, STAY reference clinics, senior signs check, monthly email, newsroom, rescues, Instagram, scorecard and vet routing; breed clubs.

  3. Days 61 to 904 ideas

    Ask-your-vet launch system, yearly senior dog report, insurer partnerships and an FDA process tracker.

The research behind the plan

3 research areas, each summarised in a few lines. Open any of them for the full detail.

Customers

What customers say

Customers value A serious, science-led approach to dog aging. The most cited problem: watching senior dogs decline.

  • Free CE for vets
  • Short lives of big breeds
  • In their words: “more good years”

Market

Competitive landscape

3 competitors compared: Dog Aging Project, Leap Years and Large animal-health companies (e.g. Zoetis).

  • Gap to exploit: A trusted owner resource on dog aging
  • Dog Aging Project: Not developing a product for vets to prescribe
  • Leap Years: Not an FDA-approved drug

Hiring signals

Loyal is staffing for launch. The VP of Marketing will build consumer and vet marketing for LOY-002, hone audiences, plan launch and define pre-approval metrics with a team of two (ideas 1, 2, 6, 7, 12, 13, 15). The VP…

  • Vice President, Marketing: Category building with vets and owners, launch plans and pre-approval metrics. Ideas 1, 2, 7, 15.
  • Vice President, CMC Regulatory Affairs: CMC program through approval and post-approval. Idea 21.
  • Principal Quality Assurance Specialist, External Manufacturing: Manufacturing quality ahead of supply.

From the team that wrote this playbook

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